Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14478233 | 0.88 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL16651165 | 0.86 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL9160028 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL27694357 | 0.80 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL809480 | 0.78 | ALDH1A1 (0.66) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL812445 | 0.78 | ALDH1A1 (0.66) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL4416356 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL4743348 | 0.77 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL10892501 | 0.77 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL1814058 | 0.77 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513010-B | Enzymatic process for preparing droxidopa | 意大利合成制造有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-112513010-A | Enzymatic method for preparing droxidopa | 意大利合成制造有限公司 | 2021-03-16 | — | — | CN | disclosed |
| EP-2078025-A2 | PROCESS FOR THE SYNTHESIS OF CLOPIDOGREL AND NEW FORMS OF PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | KRKA, tovarna zdravil, d.d., Novo mesto (SI) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008034912-A2 | PROCESS FOR THE SYNTHESIS OF CLOPIDOGREL AND NEW FORMS OF PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) | 2008-03-27 | — | — | WO | disclosed |
| WO-1993012091-A1 | D- AND L-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-1-CARBOXYLIC ACIDS AND THEIR DERIVATIVES CONTAINING URETHANE-TYPE N-PROTECTING GROUPS AS WELL AS A PROCESS FOR PREPARING THEM AND THE CORRESPONDING RACEMATES | Gyógyszerkutató Intézet Kft. (HU) | 1993-06-24 | — | — | WO | disclosed |
| US-4625054-A | Process for the resolution of (+)-6-methoxy-α-methyl-2-naphthaleneacetic acid into the corresponding enantiomers | SECIFARMA S.P.A. (IT) | 1986-11-25 | — | — | US | disclosed |