Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10593520 | 0.90 | EPHX1 (0.46) | TSHRALDH1A1ADH1BADH1CADH1A | |
| SCHEMBL16975497 | 0.90 | TSHR (0.36) | TSHRALDH1A1CA1CA2ADH1B | |
| Hydrochloric Acid SCHEMBL38660495 | 0.82 | EPHX1 (0.44) | TSHRALDH1A1ADH1BADH1CADH1A | |
| SCHEMBL27670693 | 0.82 | TSHR (0.36) | TSHRALDH1A1CA1CA2ADH1B | |
| Hydrochloric Acid SCHEMBL29449809 | 0.82 | EPHX1 (0.44) | TSHRALDH1A1ADH1BADH1CADH1A | |
| SCHEMBL9206621 | 0.80 | EPHX1 (0.37) | TSHRALDH1A1ADH1BADH1CADH1A | |
| SCHEMBL28012333 | 0.80 | TSHR (0.41) | TSHRALDH1A1CA1CA2ADH1B | |
| SCHEMBL31375083 | 0.79 | TSHR (0.36) | TSHRALDH1A1CA1CA2ADH1B | |
| SCHEMBL2863417 | 0.79 | EPHX1 (0.46) | TSHRALDH1A1ADH1BADH1CADH1A | |
| SCHEMBL24505605 | 0.76 | TSHR (0.38) | TSHRALDH1A1CA1CA2ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2034832-B1 | IL-8 RECEPTOR ANTAGONIST | GLAXOSMITHKLINE LLC (US) | 2013-10-02 | — | — | EP | disclosed |
| US-20090170871-A1 | IL-8 Receptor Antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-02 | — | — | US | disclosed |
| EP-2034832-A2 | IL-8 RECEPTOR ANTAGONIST | SmithKline Beecham Corporation (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007150016-A2 | IL-8 RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM CORPORATION (US) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170871-A1 | IL-8 Receptor Antagonists | CXCL8, CCR8, IL1RN | TSHR 825/4885ALDH1A1 2742/4885CA1 4090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.