Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4188339 | 0.98 | HRH3 (0.85) | HRH3ALDH1A1TSHRNPSR1 | |
| SCHEMBL4018816 | 0.92 | HRH3 (1.00) | HRH3 | |
| SCHEMBL4184767 | 0.90 | HRH3 (1.00) | HRH3ALDH1A1TSHRNPSR1 | |
| SCHEMBL4021657 | 0.89 | HRH3 (0.82) | HRH3 | |
| SCHEMBL4475308 | 0.89 | HRH3 (0.84) | HRH3 | |
| SCHEMBL4184191 | 0.88 | HRH3 (0.84) | HRH3 | |
| SCHEMBL4188505 | 0.85 | HRH3 (0.84) | HRH3ALDH1A1TSHRNPSR1 | |
| SCHEMBL4020966 | 0.85 | HRH3 (1.00) | HRH3 | |
| SCHEMBL4182572 | 0.84 | HRH3 (0.84) | HRH3ALDH1A1TSHRNPSR1 | |
| SCHEMBL4020046 | 0.83 | HRH3 (1.00) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095394-A1 | DIAZEPANES AS HISTAMINE H3 RECEPTOR ANTAGONISTS | EVOTEC NEUROSCIENCES GMBH (DE) | 2009-08-06 | — | — | WO | claimed |
| WO-2009095394-A1 | DIAZEPANES AS HISTAMINE H3 RECEPTOR ANTAGONISTS | EVOTEC NEUROSCIENCES GMBH (DE) | 2009-08-06 | — | — | WO | disclosed |