SCHEMBL4176273

SCHEMBL4176273

Br[Zn]Cc1ccc(I)cc1

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.42
IDO1 P14902 2/20 0.42
APP P05067 11/20 0.41
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
APEX1 P27695 1/20 0.34
PMP22 Q01453 1/20 0.34
PYCR1 P32322 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1980351 0.74 CYP2A6 (0.47) IDO1APPPYCR1
SCHEMBL1444597 0.72 IDO1 (0.48) IDO1
SCHEMBL4924208 0.72 IDO1 (0.48) IDO1CYP1A2
SCHEMBL127491 0.71
SCHEMBL17596168 0.71
SCHEMBL12647274 0.71
SCHEMBL6510298 0.69 CYP3A4 (0.50) CYP3A4IDO1APPCYP1A2CYP2D6
SCHEMBL5491719 0.69 CYP3A4 (0.50) CYP3A4IDO1APPCYP1A2CYP2D6
SCHEMBL2355588 0.69 CYP3A4 (0.50) CYP3A4IDO1APPCYP1A2CYP2D6
Bromide SCHEMBL3519090 0.69 TSHR (0.48) IDO1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114933758-A Quantum dot thin film material with gas-sensitive performance and application thereof 江苏烨湫传感科技有限公司 2022-08-23 CN claimed
CN-114540024-A Perovskite quantum dot material with gas-sensitive property and application thereof 江苏烨湫传感科技有限公司 2022-05-27 CN claimed
CN-114540024-B Perovskite quantum dot material with gas-sensitive performance and application thereof 江苏烨湫传感科技有限公司 2024-10-18 CN disclosed
CN-114933758-A Quantum dot thin film material with gas-sensitive performance and application thereof 江苏烨湫传感科技有限公司 2022-08-23 CN disclosed
CN-114540024-A Perovskite quantum dot material with gas-sensitive property and application thereof 江苏烨湫传感科技有限公司 2022-05-27 CN disclosed
US-20090270381-A1 Non-steroidal progesterone receptor modulators BAYER SCHERING PHARMA AG (DE) 2009-10-29 US disclosed
US-20090075989-A1 NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS BAYER SCHERING PHARMA AG (DE) 2009-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090270381-A1 Non-steroidal progesterone receptor modulators PGR, PGRMC1, PGRMC2 CYP3A4 286/4885IDO1 2679/4885APP 4728/4885
US-20090075989-A1 NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS NR5A1, CYP19A1, GPER1 CYP3A4 250/4885IDO1 1587/4885APP 4754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.