Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 0.55 |
| ▸ | PTPRC | P08575 | 5/20 | 0.54 |
| ▸ | PTPRF | P10586 | 2/20 | 0.54 |
| ▸ | CDC25B | P30305 | 2/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4192820 | 0.86 | PTPN1 (0.61) | PTPN1PTPRCPTPRFCDC25BALDH1A1 | |
| SCHEMBL4192812 | 0.82 | PTPN1 (0.54) | PTPN1PTPRCPTPRFCDC25BAPAF1 | |
| SCHEMBL1409019 | 0.82 | PTPN1 (0.54) | PTPN1PTPRCPTPRFCDC25BALDH1A1 | |
| SCHEMBL7487467 | 0.78 | PTPN1 (0.67) | PTPN1PTPRCPTPRFCDC25BCES2 | |
| SCHEMBL1772040 | 0.77 | KDM4E (0.49) | ALDH1A1ARCNR2BACE1 | |
| SCHEMBL28460266 | 0.75 | AR (0.59) | ALDH1A1ARCNR2 | |
| SCHEMBL6688709 | 0.74 | BACE1 (0.60) | PTPN1PTPRCPTPRFCDC25BALDH1A1 | |
| SCHEMBL18984697 | 0.74 | MAPK1 (0.51) | PTPRCALDH1A1ARCNR2 | |
| SCHEMBL27952438 | 0.73 | AR (0.43) | ALDH1A1ARCNR2 | |
| SCHEMBL3905368 | 0.72 | AR (0.51) | ALDH1A1ARCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090043116-A1 | HETERO-POLYCYCLIC COMPOUNDS, AND COLORING MATTERS, PIGMENTS, DYES, COLOR-CHANGING MATERIAL COMPOSITIONS, AND COLOR-CHANGING FILMS, MADE BY USING THE COMPOUNDS | IDEMITSU KOSAN CO., LTD. (JP) | 2009-02-12 | — | — | US | disclosed |
| US-20080290329-A1 | HETERO-POLYCYCLIC COMPOUNDS, AND COLORING MATTERS, PIGMENTS, DYES, COLOR-CHANGING MATERIAL COMPOSITIONS, AND COLOR-CHANGING FILMS, MADE BY USING THE COMPOUNDS | IDEMITSU KOSAN CO., LTD. (JP) | 2008-11-27 | — | — | US | disclosed |
| US-7420065-B2 | Color-changing performance does not deteriorate even after used for long time and which is prevented from being unusable due to deposition of the coloring matter during storage | IDEMITSU KOSAN CO., LTD. (JP) | 2008-09-02 | — | — | US | disclosed |
| US-20060235060-A1 | Hetero-polycyclic compounds, and coloring matters, pigments, dyes, color-changing material compositions, and color-changing films, made by using the compounds | IDEMITSU KOSAN CO., LTD. (JP) | 2006-10-19 | — | — | US | disclosed |
| EP-1593675-A1 | HETERO-POLYCYCLIC COMPOUNDS, AND COLORING MATTERS, PIGMENTS, DYES, COLOR-CHANGING MATERIAL COMPOSITIONS, AND COLOR-CHANGING FILMS, MADE BY USING THE COMPOUNDS | IDEMITSU KOSAN CO., LTD. (JP) | 2005-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080290329-A1 | HETERO-POLYCYCLIC COMPOUNDS, AND COLORING MATTERS, PIGMENTS, DYES, COLOR-CHANGING MATERIAL COMPOSITIONS, AND COLOR-CHANGING FILMS, MADE BY USING THE COMPOUNDS | PBRM1, BICRA, PARG | PTPN1 3776/4885PTPRC 2882/4885PTPRF 4202/4885 |
| US-20090043116-A1 | HETERO-POLYCYCLIC COMPOUNDS, AND COLORING MATTERS, PIGMENTS, DYES, COLOR-CHANGING MATERIAL COMPOSITIONS, AND COLOR-CHANGING FILMS, MADE BY USING THE COMPOUNDS | PBRM1, BICRA, PARG | PTPN1 3776/4885PTPRC 2882/4885PTPRF 4202/4885 |
| US-20060235060-A1 | Hetero-polycyclic compounds, and coloring matters, pigments, dyes, color-changing material compositions, and color-changing films, made by using the compounds | PBRM1, BICRA, PARG | PTPN1 3776/4885PTPRC 2882/4885PTPRF 4202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.