Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.45 |
| ▸ | PTPRC | P08575 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4192820 | 0.88 | PTPN1 (0.61) | BACE1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7721606 | 0.81 | S100A4 (0.47) | BACE1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4891285 | 0.81 | MEN1 (0.50) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL2463104 | 0.80 | BACE1 (0.66) | BACE1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1409019 | 0.78 | PTPN1 (0.54) | BACE1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11048150 | 0.77 | BACE1 (0.72) | BACE1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7480004 | 0.76 | MEN1 (0.43) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL5485068 | 0.76 | BACE1 (1.00) | BACE1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL29673492 | 0.76 | BACE1 (1.00) | BACE1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28121286 | 0.76 | BACE1 (0.60) | BACE1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004041840-A2 | PEPTIDE-BOUND CHROMOGENS USED FOR DETERMINING ENZYMATIC ACTIVITIES | C-CIT AG (CH) | 2004-05-21 | — | — | WO | disclosed |