Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4175902 | 0.73 | HTR2A (0.36) | HTR2AHTR2C | |
| SCHEMBL9747091 | 0.67 | — | — | |
| SCHEMBL23432232 | 0.63 | — | — | |
| SCHEMBL503928 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL3022081 | 0.61 | HTR2A (0.39) | HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL27442922 | 0.61 | HTR2A (0.39) | HTR2AHTR2C | |
| SCHEMBL4762498 | 0.57 | TSHR (0.36) | HTR2C | |
| SCHEMBL7155822 | 0.54 | — | — | |
| SCHEMBL24175903 | 0.53 | — | — | |
| SCHEMBL1876188 | 0.52 | CRBN (0.32) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227601-A1 | Bradykinin 1 Receptor Antagonists | AMGEN INC. (US) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227601-A1 | Bradykinin 1 Receptor Antagonists | BDKRB1, BDKRB2, VIPR1 | HTR2A 586/4885HTR2C 1015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.