⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18752814 | 1.00 | — | — | |
| SCHEMBL1243017 | 0.83 | TSHR (0.35) | — | |
| SCHEMBL24298669 | 0.81 | USP2 (0.44) | — | |
| SCHEMBL17448376 | 0.77 | — | — | |
| SCHEMBL3687753 | 0.76 | — | — | |
| SCHEMBL10454796 | 0.76 | — | — | |
| SCHEMBL11141996 | 0.74 | — | — | |
| SCHEMBL17177641 | 0.74 | — | — | |
| SCHEMBL22117219 | 0.74 | — | — | |
| SCHEMBL6901463 | 0.73 | ENPEP (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214738-B2 | Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers | ACUSHNET COMPANY (US) | 2007-05-08 | — | — | US | claimed |
| US-20050009642-A1 | Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2005-01-13 | — | — | US | claimed |
| US-10822349-B2 | Macrocyclic purines for the treatment of viral infections | Janssen Sciences Ireland Unlimited Company (IE) | 2020-11-03 | — | — | US | disclosed |
| US-20190330234-A1 | MACROCYCLIC PURINES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2019-10-31 | — | — | US | disclosed |
| US-10280180-B2 | Macrocyclic purines for the treatment of viral infections | JANSSEN SCIENCES IRELAND UC (IE) | 2019-05-07 | — | — | US | disclosed |
| EP-2872515-B1 | MACROCYCLIC PURINES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UC (IE) | 2016-06-08 | — | — | EP | disclosed |
| US-20150299221-A1 | MACROCYCLIC PURINES FOR THE TREATMENT OF VIRAL INFECTIONS | Janssen Sciences Ireland Unlimited Company (IE) | 2015-10-22 | — | — | US | disclosed |
| US-20150299221-A1 | MACROCYCLIC PURINES FOR THE TREATMENT OF VIRAL INFECTIONS | Janssen Sciences Ireland Unlimited Company (IE) | 2015-10-22 | — | — | US | disclosed |
| WO-2014009509-A1 | MACROCYCLIC PURINES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN R&D IRELAND (IE) | 2014-01-16 | — | — | WO | disclosed |
| US-20090137342-A1 | Golf Ball Layers Formed of Polyurethane-Based and Polyurea-Based Compositions Incorporating Block Copolymers | ACUSHNET COMPANY | 2009-05-28 | — | — | US | disclosed |
| US-7429629-B2 | Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers | ACUSHNET COMPANY (US) | 2008-09-30 | — | — | US | disclosed |
| US-20070197724-A1 | Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers | ACUSHNET COMPANY | 2007-08-23 | — | — | US | disclosed |
| US-7217764-B2 | Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers | ACUSHNET COMPANY (US) | 2007-05-15 | — | — | US | disclosed |
| US-7214738-B2 | Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers | ACUSHNET COMPANY (US) | 2007-05-08 | — | — | US | disclosed |
| US-7211624-B2 | Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers | ACUSHNET COMPANY (US) | 2007-05-01 | — | — | US | disclosed |
| US-7202303-B2 | Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers | ACUSHNET COMPANY (US) | 2007-04-10 | — | — | US | disclosed |
| US-20050009642-A1 | Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2005-01-13 | — | — | US | disclosed |
| US-20050009637-A1 | Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2005-01-13 | — | — | US | disclosed |
| US-20050009638-A1 | Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2005-01-13 | — | — | US | disclosed |
| US-20040262808-A1 | Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2004-12-30 | — | — | US | disclosed |