SCHEMBL4177910

SCHEMBL4177910

CCCC(C)COC(O)C(C)CCC

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
METAP1 P53582 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9730554 0.76 TSHR (0.42) TSHRHSD17B10TDP1
SCHEMBL15247826 0.74 TSHR (0.43) TSHR
SCHEMBL10691165 0.73 TSHR (0.35) TSHRHSD17B10
SCHEMBL9730393 0.72 TSHR (0.39) TSHRHSD17B10TDP1
SCHEMBL9507387 0.72 TDP1 (0.42) TSHRHSD17B10TDP1
SCHEMBL10593455 0.72 TSHR (0.50) TSHR
SCHEMBL27858224 0.71 SPHK1 (0.39) TSHR
SCHEMBL20055303 0.70 TSHR (0.40) TSHR
SCHEMBL7967655 0.70 TSHR (0.40) TSHR
SCHEMBL9153397 0.70 TSHR (0.41) TSHRHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1511498-B1 A METHOD OF TREATING HUMAN SKIN AND A SKIN CARE COMPOSITION FOR USE IN SUCH A METHOD PANTARHEI BIOSCIENCE BV (NL) 2012-11-21 EP disclosed
EP-1390041-B1 DRUG DELIVERY SYSTEM COMPRISING A TETRAHYDROXYLATED ESTROGEN FOR USE IN HORMONAL CONTRACEPTION PANTARHEI BIOSCIENCE BV (NL) 2009-11-25 EP disclosed
EP-1390042-B1 DRUG DELIVERY SYSTEM COMPRISING A TETRAHYDROXYLATED ESTROGEN FOR USE IN HORMONAL CONTRACEPTION PANTARHEI BIOSCIENCE BV (NL) 2007-11-28 EP disclosed
EP-1390040-B1 PHARMACEUTICAL COMPOSITION FOR USE IN HORMONE REPLACEMENT THERAPY PANTARHEI BIOSCIENCE BV (NL) 2007-01-03 EP disclosed
EP-1446128-B1 USE OF ESTROGENIC COMPOUNDS IN COMBINATION WITH PROGESTOGENIC COMPOUNDS IN HORMONE-REPLACEMENT THERAPY PANTARHEI BIOSCIENCE BV (NL) 2006-12-06 EP disclosed
EP-1700602-A1 Pharmaceutical composition for use in hormone replacement therapy Pantarhei Bioscience B.V. (NL) 2006-09-13 EP disclosed
EP-1390039-B1 USE OF ESTROGEN COMPOUNDS TO INCREASE LIBIDO IN WOMEN PANTARHEI BIOSCIENCE BV (NL) 2006-03-15 EP disclosed
EP-1390039-A1 USE OF ESTROGEN COMPOUNDS TO INCREASE LIBIDO IN WOMEN Pantarhei Bioscience B.V. (NL) 2004-02-25 EP disclosed
EP-1390040-A1 PHARMACEUTICAL COMPOSITION FOR USE IN HORMONE REPLACEMENT THERAPY Pantarhei Bioscience B.V. (NL) 2004-02-25 EP disclosed
WO-2002094275-A1 USE OF ESTROGEN COMPOUNDS TO INCREASE LIBIDO IN WOMEN PANTARHEI BIOSCIENCE B.V. (NL) 2002-11-28 WO disclosed
WO-2002094276-A1 PHARMACEUTICAL COMPOSITION FOR USE IN HORMONE REPLACEMENT THERAPY PANTARHEI BIOSCIENCE B.V. (NL) 2002-11-28 WO disclosed
EP-1260225-A1 A pharmaceutical composition for use in hormone replacement therapy Pantarhei Bioscience B.V. (NL) 2002-11-27 EP disclosed