Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19643118 | 0.83 | TSHR (0.48) | TSHRHSD17B10TDP1EPHX2 | |
| SCHEMBL9679319 | 0.83 | TSHR (0.48) | TSHRHSD17B10TDP1EPHX2 | |
| SCHEMBL10632086 | 0.81 | TSHR (0.46) | TSHRHSD17B10EPHX2 | |
| Calcium SCHEMBL10786902 | 0.81 | TSHR (0.46) | TSHRHSD17B10EPHX2 | |
| Lithium SCHEMBL8617111 | 0.81 | TSHR (0.46) | TSHRHSD17B10EPHX2 | |
| Magnesium SCHEMBL8460788 | 0.81 | TSHR (0.46) | TSHRHSD17B10EPHX2 | |
| Potassium SCHEMBL10629925 | 0.81 | TSHR (0.46) | TSHRHSD17B10EPHX2 | |
| SCHEMBL10789496 | 0.81 | TSHR (0.46) | TSHRHSD17B10EPHX2 | |
| Barium SCHEMBL10787198 | 0.81 | TSHR (0.46) | TSHRHSD17B10EPHX2 | |
| SCHEMBL11269945 | 0.81 | HSD17B10 (0.38) | TSHRHSD17B10TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351782-B1 | Optically active compounds liquid crystal composition containing said compound, and liquid crystal optical modulator using said composition | HITACHI LTD (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5328643-A | Electrooptic display, switches, modulators; physical and chemical stability and spontaneous polarization | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0351782-A2 | Optically active compounds liquid crystal composition containing said compound, and liquid crystal optical modulator using said composition | HITACHI, LTD. (JP) | 1990-01-24 | — | — | EP | disclosed |