SCHEMBL4178096

SCHEMBL4178096

O=S(=O)(Cl)C(F)(F)F.[N]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2582328 0.96 CA1 (0.47)
SCHEMBL21681 0.96
Methane SCHEMBL27881065 0.92
SCHEMBL16760664 0.92
Hydrochloric Acid SCHEMBL5733160 0.92
Lithium SCHEMBL31511739 0.92
Hydrochloric Acid SCHEMBL5925199 0.88 CA1 (0.41)
SCHEMBL10486665 0.85 CA1 (0.39)
SCHEMBL1146027 0.77 CA2 (0.39)
SCHEMBL10756128 0.77 CA1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090088469-A1 METHOD FOR THE PREPARATION OF CITALOPRAM H. LUNDBECK A/S (DK) 2009-04-02 US disclosed
EP-1159274-B1 METHOD FOR THE PREPARATION OF CITALOPRAM LUNDBECK & CO AS H (DK) 2003-03-26 EP disclosed
US-20020077353-A1 Method for the preparation of citalopram H. LUNDBECK A/S (DK) 2002-06-20 US disclosed
EP-1159274-A2 METHOD FOR THE PREPARATION OF CITALOPRAM H. Lundbeck A/S (DK) 2001-12-05 EP disclosed
WO-2000013648-A2 METHOD FOR THE PREPARATION OF CITALOPRAM H. LUNDBECK A/S (DK) 2000-03-16 WO disclosed