Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19153581 | 0.81 | HDAC6 (0.46) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL28101859 | 0.77 | HDAC6 (0.47) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL23995623 | 0.75 | HDAC6 (0.42) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL8737769 | 0.74 | HDAC6 (0.39) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL761358 | 0.74 | HDAC6 (0.39) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL3716921 | 0.74 | HDAC6 (0.39) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL20916878 | 0.72 | HDAC6 (0.38) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL28394 | 0.72 | HDAC6 (0.38) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL1771686 | 0.72 | HDAC6 (0.38) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL1454438 | 0.72 | HDAC6 (0.38) | HDAC6HDAC1HDAC2DGAT1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8597867-B2 | Lactone copolymer and radiation-sensitive resin composition | JSR CORPORATION (JP) | 2013-12-03 | — | — | US | disclosed |
| US-20090053649-A1 | Lactone copolymer and radiation-sensitive resin composition | JSR CORPORATION | 2009-02-26 | — | — | US | disclosed |
| EP-1757628-A1 | LACTONE COPOLYMER AND RADIATION-SENSITIVE RESIN COMPOSITION | JSR Corporation (JP) | 2007-02-28 | — | — | EP | disclosed |