Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 10/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.42 |
| ▸ | CASP1 | P29466 | 8/20 | 0.42 |
| ▸ | CASP7 | P55210 | 8/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | SIK1 | P57059 | 2/20 | 0.42 |
| ▸ | SIK2 | Q9H0K1 | 2/20 | 0.42 |
| ▸ | SIK3 | Q9Y2K2 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAK | O14976 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4187838 | 0.92 | TNK2 (0.50) | TNK2USP2MEN1KMT2ASIK1 | |
| SCHEMBL4173640 | 0.92 | TNK2 (0.44) | TNK2USP2MEN1KMT2ACYP1A2 | |
| SCHEMBL4178516 | 0.87 | TNK2 (0.48) | TNK2SIK1SIK2SIK3GAK | |
| SCHEMBL4186207 | 0.86 | TNK2 (0.44) | TNK2SIK1SIK2SIK3ABL1 | |
| SCHEMBL4180893 | 0.85 | TNK2 (0.53) | TNK2SIK1SIK2SIK3ABL1 | |
| SCHEMBL4173629 | 0.84 | TNK2 (0.46) | TNK2SIK1SIK2SIK3ABL1 | |
| SCHEMBL4183495 | 0.83 | WEE1 (0.52) | TNK2ABL1SRC | |
| SCHEMBL4193017 | 0.82 | CCND1 (0.44) | TNK2CYP1A2CASP1CASP7CYP3A4 | |
| SCHEMBL4183089 | 0.82 | TNK2 (0.50) | TNK2SIK1SIK2SIK3ABL1 | |
| SCHEMBL4178712 | 0.82 | TNK2 (0.43) | TNK2SIK1SIK2SIK3PAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036472-A1 | AZABICYCLO DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-02-05 | — | — | US | claimed |
| EP-1846403-A1 | AZABICYCLO DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | Ranbaxy Laboratories Limited (IN) | 2007-10-24 | — | — | EP | claimed |
| WO-2006082492-A1 | AZABICYCLO DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-10 | — | — | WO | claimed |
| US-20090036472-A1 | AZABICYCLO DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-02-05 | — | — | US | disclosed |
| US-20090036472-A1 | AZABICYCLO DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-02-05 | — | — | US | disclosed |
| US-20090036472-A1 | AZABICYCLO DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036472-A1 | AZABICYCLO DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | IL1B, TPMT, IL1R1 | TNK2 994/4885USP2 4493/4885MEN1 3606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.