Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 18/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13686583 | 1.00 | CCR2 (0.58) | CCR2CHRM1KCNH2MEN1KMT2A | |
| SCHEMBL13686557 | 0.88 | CHRM1 (0.59) | CCR2CHRM1 | |
| SCHEMBL4166296 | 0.88 | CHRM1 (0.59) | CCR2CHRM1 | |
| SCHEMBL3873787 | 0.85 | CCR2 (0.66) | CCR2KCNH2MEN1KMT2A | |
| SCHEMBL3873789 | 0.85 | CCR2 (0.66) | CCR2KCNH2MEN1KMT2A | |
| SCHEMBL13853135 | 0.85 | RXFP1 (0.48) | CCR2CHRM1KCNH2 | |
| SCHEMBL13853136 | 0.85 | RXFP1 (0.48) | CCR2CHRM1KCNH2 | |
| SCHEMBL3874185 | 0.77 | CCR2 (0.71) | CCR2KCNH2 | |
| SCHEMBL3874180 | 0.77 | CCR2 (0.71) | CCR2KCNH2 | |
| SCHEMBL3874207 | 0.77 | CCR2 (0.72) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090130090-A1 | N-amide Derivatives of 8-Azabicyclo[3.2.1]OCT-3-YL AS CCR1 Antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090130090-A1 | N-amide Derivatives of 8-Azabicyclo[3.2.1]OCT-3-YL AS CCR1 Antagonists | CCR1, CCR3, CCR8 | CCR2 6/4885CHRM1 394/4885KCNH2 3671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.