Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4179001 | 1.00 | KMT2A (0.63) | KMT2AHPGDEPHX1RAB9ANPC1 | |
| SCHEMBL13043831 | 0.98 | KMT2A (0.59) | KMT2AHPGDEPHX1RAB9ANPC1 | |
| Propionamide SCHEMBL6017481 | 0.87 | KMT2A (0.50) | KMT2AHPGDEPHX1RAB9ANPC1 | |
| SCHEMBL11356392 | 0.86 | HPGD (0.53) | KMT2AHPGDEPHX1RAB9ANPC1 | |
| SCHEMBL18090914 | 0.84 | KMT2A (0.61) | KMT2AHPGDEPHX1RAB9ANPC1 | |
| SCHEMBL26332838 | 0.81 | KMT2A (0.57) | KMT2AHPGDEPHX1RAB9ANPC1 | |
| SCHEMBL24235893 | 0.79 | KMT2A (0.61) | KMT2AHPGDEPHX1RAB9ANPC1 | |
| SCHEMBL14456383 | 0.79 | KMT2A (0.61) | KMT2AHPGDEPHX1RAB9ANPC1 | |
| SCHEMBL14606389 | 0.79 | KMT2A (0.61) | KMT2AHPGDEPHX1RAB9ANPC1 | |
| SCHEMBL1779033 | 0.79 | KMT2A (0.61) | KMT2AHPGDEPHX1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285785-B | Synthetic method of hydroximic acid collecting agent | 广东省资源综合利用研究所 | 2023-04-07 | — | — | CN | disclosed |
| CN-108929246-B | Method for preparing hydroximic acid derivatives by solid-state method | 湖南中医药大学 | 2021-07-02 | — | — | CN | disclosed |
| CN-111285785-A | Synthetic method of hydroximic acid collecting agent | 广东省资源综合利用研究所 | 2020-06-16 | — | — | CN | disclosed |
| EP-1727516-B1 | COMPOSITION COMPRISING AN HDAC INHIBITOR IN COMBINATION WITH A RETINOID | DSM IP ASSETS BV (NL) | 2014-05-14 | — | — | EP | disclosed |
| US-8227516-B2 | Compounds as histone deacetylase inhibitors | 4SC DISCOVERY GMBH (DE) | 2012-07-24 | — | — | US | disclosed |
| US-8227516-B2 | Compounds as histone deacetylase inhibitors | 4SC DISCOVERY GMBH (DE) | 2012-07-24 | — | — | US | disclosed |
| US-8227516-B2 | Compounds as histone deacetylase inhibitors | 4SC DISCOVERY GMBH (DE) | 2012-07-24 | — | — | US | disclosed |
| CN-1933802-B | Composition comprising an hdac inhibitor in combination with a retinoid | DSM IP ASSETS BV | 2011-07-06 | — | — | CN | disclosed |
| US-20090088478-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | 4SC DISCOVERY GMBH (DE) | 2009-04-02 | — | — | US | disclosed |
| US-20090088478-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | 4SC DISCOVERY GMBH (DE) | 2009-04-02 | — | — | US | disclosed |
| CN-1933802-A | Composition comprising an hdac inhibitor in combination with a retinoid | DSM IP ASSETS BV (NL) | 2007-03-21 | — | — | CN | disclosed |
| US-20050176686-A1 | Novel compounds as histone deacetylase inhibitors | 4SC AG (DE) | 2005-08-11 | — | — | US | disclosed |
| EP-1523470-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | 4SC AG (DE) | 2005-04-20 | — | — | EP | disclosed |
| CN-1183107-C | Alkynyl containing hydroxamic acid compounds as TACE inhibitors | ���Ͽع�����˾ | 2005-01-05 | — | — | CN | disclosed |
| WO-2004009536-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | 4SC AG (DE) | 2004-01-29 | — | — | WO | disclosed |
| WO-2004009536-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | 4SC AG (DE) | 2004-01-29 | — | — | WO | disclosed |
| EP-1299377-A2 | SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-04-09 | — | — | EP | disclosed |
| CN-1337945-A | Alkynyl containing hydroxamic acid compounds as TACE inhibitors | AMERICAN CYANAMID CO (US) | 2002-02-27 | — | — | CN | disclosed |
| WO-2002000641-A2 | SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2002-01-03 | — | — | WO | disclosed |
| US-4611053-A | METAL CHELATE COMPOUNDS, DETOXIFICATION OF BLOOD | SASA MICHIYUKI MITCH | 1986-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176686-A1 | Novel compounds as histone deacetylase inhibitors | HDAC3, HDAC1, HDAC2 | KMT2A 95/4885HPGD 1495/4885EPHX1 2932/4885 |
| US-20090088478-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC11, HDAC5 | KMT2A 99/4885HPGD 556/4885EPHX1 3499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.