Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | BCHE | P06276 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | PARP1 | P09874 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957423 | 0.83 | OPRM1 (0.63) | KDM4EMEN1KMT2ABCHEALDH1A1 | |
| SCHEMBL11847836 | 0.83 | OPRM1 (0.63) | KDM4EMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL3646720 | 0.82 | CA1 (0.66) | KDM4EALDH1A1NPC1PARP1MMP13 | |
| Hydrochloric Acid SCHEMBL11847451 | 0.81 | OPRM1 (0.61) | KDM4EMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL3963921 | 0.81 | CA1 (0.57) | KDM4EMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL4165717 | 0.80 | CHEK1 (0.50) | KDM4EMEN1KMT2AALDH1A1PARP1 | |
| SCHEMBL29194688 | 0.80 | BCHE (0.80) | KDM4EMEN1KMT2ABCHEALDH1A1 | |
| SCHEMBL3692972 | 0.79 | OPRM1 (0.76) | KDM4EBCHEALDH1A1NPC1 | |
| SCHEMBL18114970 | 0.78 | CHRM2 (0.77) | KDM4EMEN1KMT2ABCHEALDH1A1 | |
| SCHEMBL4916089 | 0.78 | CHRM2 (0.81) | KDM4EMEN1KMT2ABCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079525-A1 | CALCIUM RECEPTOR MODULATING AGENTS | Amgen Inc. (US) | 2009-07-22 | — | — | EP | claimed |
| WO-2008057282-A1 | CALCIUM RECEPTOR MODULATING AGENTS | AMGEN INC. (US) | 2008-05-15 | — | — | WO | claimed |