SCHEMBL4180262

SCHEMBL4180262

COC(=O)c1cc(NCc2c(C)cccc2C)c2nc(C)c(C)n2c1

nearest known ligand 0.73

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 20/20 0.73
CYP2C9 P11712 20/20 0.73
CYP2D6 P10635 10/20 0.73
CYP2C19 P33261 8/20 0.70
CYP1A2 P05177 7/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4886755 0.93 CYP3A4 (0.82) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL6349099 0.91 CYP3A4 (0.70) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL3274522 0.90 CYP3A4 (0.74) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL2368041 0.89 CYP3A4 (0.68) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL1816215 0.89 CYP3A4 (0.86) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL31706363 0.87 CYP3A4 (0.70) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL4161190 0.86 CYP3A4 (0.80) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL14290065 0.85 CYP3A4 (0.68) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL20987042 0.84 CYP3A4 (0.61) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
Linaprazan SCHEMBL1138353 0.84 CYP3A4 (1.00) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025215593-A1 AN IMPROVED PROCESS FOR PREPARATION OF ZASTAPRAZAN HETERO LABS LIMITED (IN) 2025-10-16 WO claimed
WO-2025215593-A1 AN IMPROVED PROCESS FOR PREPARATION OF ZASTAPRAZAN HETERO LABS LIMITED (IN) 2025-10-16 WO disclosed
WO-2025215593-A1 AN IMPROVED PROCESS FOR PREPARATION OF ZASTAPRAZAN HETERO LABS LIMITED (IN) 2025-10-16 WO disclosed
US-20090247755-A1 Process for Preparing a Substituted Imidazopyridine Compound ELMAN BJORN 2009-10-01 US disclosed
US-20090247755-A1 Process for Preparing a Substituted Imidazopyridine Compound ELMAN BJORN 2009-10-01 US disclosed
US-20090247755-A1 Process for Preparing a Substituted Imidazopyridine Compound ELMAN BJORN 2009-10-01 US disclosed
US-20060063797-A1 Process for preparing a substituted imidazopyridine compound ELMAN BJORN 2006-03-23 US disclosed
EP-1073657-B1 IMIDAZO PYRIDINE DERIVATIVES WHICH INHIBIT GASTRIC ACID SECRETION ASTRAZENECA AB (SE) 2005-12-07 EP disclosed
US-6900324-B2 Process for preparing a substituted imidazopyridine compound ASTRAZENECA AB (SE) 2005-05-31 US disclosed
EP-1317455-B9 PROCESS FOR PREPARING A SUBSTITUTED IMIDAZOPYRIDINE COMPOUND ASTRAZENECA AB (SE) 2004-11-17 EP disclosed
EP-1317455-B1 PROCESS FOR PREPARING A SUBSTITUTED IMIDAZOPYRIDINE COMPOUND ASTRAZENECA AB (SE) 2004-08-04 EP disclosed
US-20040039013-A1 Process for preparing a substituted imidazopyridine compound ASTRAZENECA AB (SE) 2004-02-26 US disclosed
EP-1317455-A1 PROCESS FOR PREPARING A SUBSTITUTED IMIDAZOPYRIDINE COMPOUND AstraZeneca AB (SE) 2003-06-11 EP disclosed
WO-2002020523-A1 PROCESS FOR PREPARING A SUBSTITUTED IMIDAZOPYRIDINE COMPOUND ASTRAZENECA AB (SE) 2002-03-14 WO disclosed
US-6313137-B1 FOR THERAPY AND PROPHYLAXIS OF GASTROINTESTINAL INFLAMMATORY DISEASES ASTRAZENECA AB (SE) 2001-11-06 US disclosed
WO-1999055706-A9 IMIDAZO PYRIDINE DERIVATIVES WHICH INHIBIT GASTRIC ACID SECRETION ASTRA AB (SE) 2000-03-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060063797-A1 Process for preparing a substituted imidazopyridine compound NISCH, CYP1B1, CYP1A2 CYP3A4 8/4885CYP2C9 121/4885CYP2D6 24/4885
US-20090247755-A1 Process for Preparing a Substituted Imidazopyridine Compound NISCH, CYP1A2, CYP1B1 CYP3A4 13/4885CYP2C9 133/4885CYP2D6 23/4885
US-20040039013-A1 Process for preparing a substituted imidazopyridine compound CYP1B1, BRD1, SKP1 CYP3A4 24/4885CYP2C9 261/4885CYP2D6 17/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.