SCHEMBL3274522

SCHEMBL3274522

Cc1cccc(C)c1CNc1cc(C(=O)O)cn2c(C)c(C)nc12

nearest known ligand 0.74

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 20/20 0.74
CYP2C9 P11712 20/20 0.74
CYP2D6 P10635 10/20 0.74
CYP2C19 P33261 8/20 0.71
CYP1A2 P05177 7/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4170085 0.93 CYP3A4 (0.83) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL31706363 0.92 CYP3A4 (0.70) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL5257853 0.91 CYP3A4 (0.63) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL4180262 0.90 CYP3A4 (0.73) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL1816215 0.90 CYP3A4 (0.86) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL5258282 0.89 CYP3A4 (0.74) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL14290065 0.89 CYP3A4 (0.68) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL5257152 0.89 CYP3A4 (0.59) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL6349099 0.88 CYP3A4 (0.70) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL2368041 0.86 CYP3A4 (0.68) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025215593-A1 AN IMPROVED PROCESS FOR PREPARATION OF ZASTAPRAZAN HETERO LABS LIMITED (IN) 2025-10-16 WO claimed
US-20050222193-A1 Novel combination for the treatment of airway disorders ALTANA PHARMA AG (DE) 2005-10-06 US claimed
EP-1506016-A2 NEW COMBINATION OF REVERSIBLE PROTON PUMP INHIBITORS AND AIRWAY THERAPEUTICS FOR TREATING AIRWAY DISORDERS ALTANA Pharma AG (DE) 2005-02-16 EP claimed
EP-1105391-B1 Imidazo[1,2-a]pyridine compounds that inhibit gastric acid secretion, pharmaceutical compositions thereof, and processes for thier preparation ASTRAZENECA AB (SE) 2004-10-27 EP claimed
WO-2003094967-A2 NEW COMBINATION OF REVERSIBLE PROTON PUMP INHIBITORS AND AIRWAY THERAPEUTICS FOR TREATING AIRWAY DISORDERS ALTANA PHARMA AG (DE) 2003-11-20 WO claimed
WO-2025215593-A1 AN IMPROVED PROCESS FOR PREPARATION OF ZASTAPRAZAN HETERO LABS LIMITED (IN) 2025-10-16 WO disclosed
EP-4563577-A1 NOVEL SALT OF IMIDAZO[1,2-A]PYRIDINE COMPOUND, CRYSTALLINE FORM THEREOF, AND PREPARATION METHOD Jeil Pharmaceutical Co., Ltd. (KR) 2025-06-04 EP disclosed
US-10696671-B2 Imidazo[1,2-A]pyridine derivatives, methods for preparing the same and use thereof JEIL PHARMACEUTICAL CO., LTD. (KR) 2020-06-30 US disclosed
US-20190152971-A1 Imidazo[1,2-A]Pyridine Derivatives, Methods for Preparing the Same and Use Thereof JEIL PHARMACEUTICAL CO., LTD. (KR) 2019-05-23 US disclosed
US-7691875-B2 Imidazopyridine compounds, processes for their preparation and therapeutic uses thereof ASTRAZENECA AB (SE) 2010-04-06 US disclosed
US-7691875-B2 Imidazopyridine compounds, processes for their preparation and therapeutic uses thereof ASTRAZENECA AB (SE) 2010-04-06 US disclosed
US-7691875-B2 Imidazopyridine compounds, processes for their preparation and therapeutic uses thereof ASTRAZENECA AB (SE) 2010-04-06 US disclosed
US-20070066642-A1 Novel imidazopyridine compound ii with therapeutic effect ASTRAZENECA AB (SE) 2007-03-22 US disclosed
EP-1641793-A1 NOVEL IMIDAZOPYRIDINE COMPOUND II WITH THERAPEUTIC EFFECT AstraZeneca AB (SE) 2006-04-05 EP disclosed
US-20050222193-A1 Novel combination for the treatment of airway disorders ALTANA PHARMA AG (DE) 2005-10-06 US disclosed
EP-1506016-A2 NEW COMBINATION OF REVERSIBLE PROTON PUMP INHIBITORS AND AIRWAY THERAPEUTICS FOR TREATING AIRWAY DISORDERS ALTANA Pharma AG (DE) 2005-02-16 EP disclosed
WO-2004113340-A1 NOVEL IMIDAZOPYRIDINE COMPOUND III WITH THERAPEUTIC EFFECT ASTRAZENECA AB (SE) 2004-12-29 WO disclosed
WO-2004113339-A1 NOVEL IMIDAZOPYRIDINE COMPOUND II WITH THERAPEUTIC EFFECT ASTRAZENECA AB (SE) 2004-12-29 WO disclosed
WO-2004113338-A1 NOVEL IMIDAZOPYRIDINE COMPOUND I WITH THERAPEUTIC EFFECT ASTRAZENECA AB (SE) 2004-12-29 WO disclosed
WO-2003094967-A2 NEW COMBINATION OF REVERSIBLE PROTON PUMP INHIBITORS AND AIRWAY THERAPEUTICS FOR TREATING AIRWAY DISORDERS ALTANA PHARMA AG (DE) 2003-11-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070066642-A1 Novel imidazopyridine compound ii with therapeutic effect GIPR, HRH2, VIP CYP3A4 1521/4885CYP2C9 3408/4885CYP2D6 2510/4885
US-10696671-B2 Imidazo[1,2-A]pyridine derivatives, methods for preparing the same and use thereof HRH2, GIPR, HRH4 CYP3A4 145/4885CYP2C9 477/4885CYP2D6 327/4885
US-20190152971-A1 Imidazo[1,2-A]Pyridine Derivatives, Methods for Preparing the Same and Use Thereof GIPR, PGC, VIP CYP3A4 987/4885CYP2C9 1375/4885CYP2D6 2024/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.