SCHEMBL4180590

SCHEMBL4180590

CC(=O)OOc1ccc(Cl)c2cccnc12

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 12/20 0.74
ALOX12 P18054 3/20 0.74
TDP1 Q9NUW8 2/20 0.74
CYP3A4 P08684 1/20 0.74
GAA P10253 2/20 0.61
PKM P14618 1/20 0.59
MAPT P10636 6/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
NPSR1 Q6W5P4 3/20 0.55
HTT P42858 1/20 0.55
L3MBTL1 Q9Y468 4/20 0.54
HSP90AA1 P07900 3/20 0.54
CCR6 P51684 2/20 0.54
ALDH1A1 P00352 3/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
HSD17B10 Q99714 2/20 0.53
HPGD P15428 1/20 0.51
TSHR P16473 1/20 0.51
TP53 P04637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloroacetoxyquinoline SCHEMBL3691077 0.85 KDM4E (1.00) KDM4EALOX12TDP1CYP3A4GAA
SCHEMBL26602580 0.85 KDM4E (0.61) KDM4EALOX12TDP1CYP3A4GAA
SCHEMBL21623631 0.84 KDM4E (0.60) KDM4EALOX12TDP1CYP3A4GAA
SCHEMBL2476668 0.81 PKM (0.57) KDM4EALOX12TDP1CYP3A4GAA
SCHEMBL21049498 0.81 KDM4E (0.71) KDM4EALOX12TDP1CYP3A4GAA
SCHEMBL30493067 0.81 KDM4E (0.71) KDM4EALOX12TDP1CYP3A4GAA
SCHEMBL17859581 0.80 PKM (0.74) KDM4EALOX12TDP1CYP3A4GAA
SCHEMBL27850572 0.80 KDM4E (0.58) KDM4EALOX12TDP1CYP3A4GAA
SCHEMBL21582022 0.80 MAPT (0.70) KDM4EALOX12TDP1CYP3A4GAA
SCHEMBL29444248 0.79 PKM (0.55) KDM4EALOX12TDP1CYP3A4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118255715-A Preparation method of 1-methyl hexyl (5-chloro-8-quinolinyloxy) acetate 无锡颐景丰科技有限公司 2024-06-28 CN claimed
CN-113367128-B Composition containing R-oxadiazolyl aryl formamide compound and safener and application thereof 江苏清原农冠杂草防治有限公司 2023-04-28 CN claimed
CN-113367128-A Composition containing R-type oxadiazolyl aryl formamide compound and safener and application thereof 江苏清原农冠杂草防治有限公司 2021-09-10 CN claimed
CN-102718706-A Preparation method for 2-(5-chlorine-8-quinoline oxygen group) acetic acid UNIV SHAOXING 2012-10-10 CN claimed
CN-1589100-A Herbicidal composition comprising benzoylpyrazoles and safeners BAYER CROPSCIENCE GMBH (DE) 2005-03-02 CN claimed
US-6124240-A Combinations of sulfonylurea herbicides and safeners HOECHST AGREVO GMBH (DE) 2000-09-26 US claimed
WO-2000011954-A1 HERBICIDAL METHOD AVENTIS CROPSCIENCE S.A. (FR) 2000-03-09 WO claimed
EP-0533057-B1 Selective herbicidal agent in the form of concentrated microemulsions HOECHST SCHERING AGREVO GMBH (DE) 1997-12-29 EP claimed
US-5622910-A CROP PROTECTION AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1997-04-22 US claimed
CN-115768752-B Substituted isophthalic acid diamides 拜耳公司 2025-04-22 CN disclosed
CN-116250539-B Ternary weeding composition containing fenpyrazamine and application thereof 青岛清原化合物有限公司 2025-03-18 CN disclosed
CN-118974025-A Substituted 2-amino-oxazines and salts thereof and their use as herbicidal agents 拜耳公司 2024-11-15 CN disclosed
CN-113302187-B Substituted pyridyloxy benzenes and salts thereof, and their use as herbicides 拜耳公司 2024-10-29 CN disclosed
CN-114071999-B 1-Phenyl-5-azinylpyrazolyl-3-oxyalkyl acids and their use for controlling unwanted plant growth 拜耳公司 2024-08-27 CN disclosed
CN-1309533-A Herbicidal composition AVENTIS CORPSCIENCE GMBH (DE) 2001-08-22 CN disclosed
US-20010011063-A1 Substituted 2,4-diamino-1,3,5-triazines, processes for their preparation and their use as herbicides and plant growth regulators AVENTIS CROPSCIENCE GMBH (DE) 2001-08-02 US disclosed
WO-2000011954-A1 HERBICIDAL METHOD AVENTIS CROPSCIENCE S.A. (FR) 2000-03-09 WO disclosed
CN-1239867-A Herbicidal compositions comprising N- [ (4, 6-dimethoxypyrimidin-2-yl) aminocarbonyl ] -5-methylsulphinylaminomethyl-2-alkoxycarbonylbenzenesulfonamide HOECHST SCHERING AGREVO GMBH (DE) 1999-12-29 CN disclosed
US-5733847-A Selective herbicidal compositions in the form of concentrated microemulsions HOECHST AKTIENGESELLSCHAFT (DE) 1998-03-31 US disclosed
US-5571772-A Mixtures of triazine sulfonylurea herbicides and pyrazoline safeners HOECHST SCHERING AGREVO GMBH (DE) 1996-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010011063-A1 Substituted 2,4-diamino-1,3,5-triazines, processes for their preparation and their use as herbicides and plant growth regulators DDT, DAZAP1, SAT1 KDM4E 545/4885ALOX12 4493/4885TDP1 2471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.