Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | RXRA | P19793 | 1/20 | 0.64 |
| ▸ | MPC2 | O95563 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19849386 | 0.91 | PPARG (0.60) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL20697606 | 0.91 | PPARG (0.67) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL826836 | 0.90 | PPARG (0.70) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL24363120 | 0.88 | PPARG (0.61) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL12961255 | 0.87 | PPARG (0.61) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL12930840 | 0.87 | PPARG (0.61) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL12930819 | 0.87 | PPARG (0.61) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL1054873 | 0.87 | PPARG (0.66) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL18323953 | 0.87 | PPARG (0.66) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL12930891 | 0.85 | PPARG (0.59) | PPARGCYP3A4RXRAMPC2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118514-A1 | PROCESSES FOR PREPARING PIOGLITAZONE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | DR. REDDY'S LABORATORIES, INC. | 2009-05-07 | — | — | US | claimed |
| WO-2012166614-A2 | THIOCARBAMATE AND SULFONAMIDE HYDROXAMATE INHIBITORS OF INSULIN-DEGRADING ENZYME | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2012-12-06 | — | — | WO | disclosed |
| US-20090118514-A1 | PROCESSES FOR PREPARING PIOGLITAZONE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | DR. REDDY'S LABORATORIES, INC. | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118514-A1 | PROCESSES FOR PREPARING PIOGLITAZONE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | DPP4, SLC5A2, SLC5A1 | PPARG 4/4885CYP3A4 52/4885RXRA 381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.