Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 10/20 | 0.43 |
| ▸ | TUBB | P07437 | 10/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 10/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 10/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 10/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 10/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 10/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 10/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 10/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 10/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 10/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 10/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 10/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 10/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 10/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4173366 | 0.89 | FYN (0.45) | FYNTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4170604 | 0.87 | FYN (0.44) | FYNTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4181712 | 0.85 | FYN (0.42) | FYNTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4179136 | 0.80 | TUBB4A (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4181586 | 0.80 | TUBB4A (0.55) | FYNTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4185677 | 0.79 | FYN (0.40) | FYNTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4181327 | 0.78 | TUBB4A (0.68) | FYNTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4175522 | 0.75 | TUBB4A (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4175608 | 0.74 | MEN1 (0.41) | FYNTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4181118 | 0.74 | TUBB4A (0.47) | FYNTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318438-A1 | Heterocyclic compounds and their use as anticancer agents | CHEN XIAOLING | 2009-12-24 | — | — | US | disclosed |
| US-20090048301-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS ANTICANCER AGENTS | IMCLONE SYSTEMS INCORPORATED (US) | 2009-02-19 | — | — | US | disclosed |
| WO-2005004818-A2 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS ANTICANCER AGENTS | IMCLONE SYSTEMS INCORPORATED (US) | 2005-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048301-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS ANTICANCER AGENTS | TP53, MCL1, VHL | FYN 2776/4885TUBB4A 777/4885TUBB 766/4885 |
| US-20090318438-A1 | Heterocyclic compounds and their use as anticancer agents | TP53, MCL1, VHL | FYN 2776/4885TUBB4A 777/4885TUBB 766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.