SCHEMBL4181359

SCHEMBL4181359

O=P(O)(O)Oc1c(O)c(OP(=O)(O)O)c(OP(=O)(O)O)c(OP(=O)(O)O)c1OP(=O)(O)O

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 12/20 0.50
INPP5A Q14642 6/20 0.50
AKT1 P31749 1/20 0.50
INPP5B P32019 2/20 0.46
SRC P12931 5/20 0.39
FDPS P14324 1/20 0.35
BLM P54132 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
KDM4E B2RXH2 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
PDE3A Q14432 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4181314 0.87 INPPL1 (0.60) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL5705481 0.74 INPPL1 (0.43) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL28505708 0.72 INPPL1 (0.41) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL18045507 0.71 INPPL1 (0.75) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL4186925 0.70 INPPL1 (0.71) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL28786310 0.69 INPPL1 (0.61) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL5370752 0.69 INPPL1 (0.50) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL25268769 0.69 INPPL1 (0.48) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL3487751 0.69 INPPL1 (0.48) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL574460 0.69 INPPL1 (0.48) INPPL1INPP5AAKT1INPP5BSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090098589-A1 Method DUPONT NUTRITION BIOSCIENCES APS (DK) 2009-04-16 US disclosed
EP-1888771-A2 METHOD FOR DETERMINING PHYTASE ACTIVITY DANISCO A/S (DK) 2008-02-20 EP disclosed
WO-2006123254-A2 METHOD FOR DETERMINING PHYTASE ACTIVITY DANISCO A/S (DK) 2006-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090098589-A1 Method ALPL, PPA1, ITPA INPPL1 40/4885INPP5A 15/4885AKT1 4656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.