E637

E637

SCHEMBL41817

CCc1occc(=O)c1O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.55
LMNA P02545 1/20 0.55
APP P05067 6/20 0.38
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
MAPK1 P28482 1/20 0.36
FTO Q9C0B1 2/20 0.36
MMP1 P03956 1/20 0.35
MMP3 P08254 1/20 0.35
MMP7 P09237 1/20 0.35
MMP9 P14780 1/20 0.35
MMP8 P22894 1/20 0.35
MMP12 P39900 1/20 0.35
MMP13 P45452 1/20 0.35
POLB P06746 2/20 0.33
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALOX5 P09917 1/20 0.32
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
E637 SCHEMBL1870685 1.00 KDM4E (0.55) KDM4ELMNAAPPGABRA1GABRB2
E637 SCHEMBL23309786 0.98 KDM4E (0.53) KDM4ELMNAAPPGABRA1GABRB2
E637 SCHEMBL27635951 0.98 KDM4E (0.53) KDM4ELMNAAPPGABRA1GABRB2
E637 SCHEMBL6657728 0.98 KDM4E (0.53) KDM4ELMNAAPPGABRA1GABRB2
E637 SCHEMBL8026696 0.98 KDM4E (0.53) KDM4ELMNAAPPGABRA1GABRB2
E637 SCHEMBL14990891 0.93 KDM4E (0.48) KDM4ELMNAAPPGABRA1GABRB2
E637 SCHEMBL290806 0.91 LMNA (0.72) KDM4ELMNAAPPGABRA1GABRB2
E637 SCHEMBL11019418 0.89 LMNA (0.70) KDM4ELMNAAPPMAPK1FTO
SCHEMBL9625161 0.84 KDM4E (0.52) KDM4ELMNAAPPMAPK1FTO
SCHEMBL9625506 0.81 KDM4E (0.48) KDM4ELMNAAPPALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 21390 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070827-A Salt baked flavored chicken energy chewable tablet and preparation method thereof 华南理工大学 2026-05-22 CN claimed
WO-2026104604-A1 SOLID FRAGRANCE COMPOSITION FIRMENICH SA (CH) 2026-05-21 WO claimed
EP-4745197-A1 ASPHALT ADDITIVE, AND ASPHALT COMPOSITION AND PREPARATION METHOD THEREFOR China Petroleum & Chemical Corporation (CN) 2026-05-20 EP claimed
EP-4744766-A1 MICROCAPSULE, PREPARATION METHOD THEREFOR, AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2026-05-20 EP claimed
CN-122030576-A Walnut essence and preparation method thereof 杭州盛华香料有限公司 2026-05-15 CN claimed
WO-2026098326-A1 AEROSOL-GENERATING ARTICLE, AEROSOL-GENERATING SYSTEM, AND MANUFACTURING METHOD FOR AEROSOL-GENERATING SECTION 爱奇迹创造有限公司 2026-05-15 WO claimed
CN-122004513-A Fragrant and sweet flavor substance, preparation method thereof and aerosol matrix 东莞市吉纯生物技术有限公司 2026-05-12 CN claimed
CN-122004515-A Method for enhancing sweetness of cigarette smoke based on sweet synergism 河南中烟工业有限责任公司 2026-05-12 CN claimed
CN-122004370-A Emulsified liquid fishy smell and preparation method and application thereof 成都大帝汉克生物科技有限公司 2026-05-12 CN claimed
US-12582134-B2 Non-dairy creamer and method of making the same CARGILL, INCORPORATED (US) 2026-03-24 US claimed
US-4082717-A OXIDATION, HYDROLYSIS PFIZER INC. (US) 1978-04-04 US claimed
US-4076854-A ADJUVANTS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-02-28 US claimed
US-4067962-A ANTISTAINING THE PROCTER & GAMBLE COMPANY (US) 1978-01-10 US claimed
US-4055691-A Uses of α-oxy(oxo) sulfides and ethers in foodstuffs and flavors for foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-10-25 US claimed
US-4053655-A Uses of α-oxy(oxo) sulfides and ethers in foodstuffs and flavors for foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-10-11 US claimed
US-4053654-A Uses of α-oxy(oxo) sulfides and ethers in foodstuffs and flavors for foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-10-11 US claimed
US-4044164-A BERRY, CEREAL, NUT, BROCCOLI, ONION, CITRUS, JASMIN, MILK CARAMEL, GRAPE INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-08-23 US claimed
US-4018907-A Coloring food with iron-complexes GENERAL FOODS CORPORATION (US) 1977-04-19 US claimed
US-3988487-A Foodstuff flavoring compositions comprising alkylidene alkenals and processes for preparing same as well as flavoring compositions for use in such foodstuff INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-10-26 US claimed
US-3939288-A 3-HYDROXY-2-ETHYL-GAMMA-PYRONE ARMOUR AND COMPANY (US) 1976-02-17 US claimed