SCHEMBL4182170

SCHEMBL4182170

Cc1cc(SC(CCCc2ccccc2)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1O

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.75
PPARA Q07869 5/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11926059 0.89 PPARD (0.73) PPARDPPARA
SCHEMBL11926062 0.89 PPARD (0.73) PPARDPPARA
SCHEMBL15097770 0.86 PPARD (0.74) PPARDPPARA
SCHEMBL4174621 0.86 PPARD (1.00) PPARDPPARA
SCHEMBL15097828 0.84 PPARD (0.70) PPARDPPARA
SCHEMBL4183756 0.83 PPARD (1.00) PPARDPPARA
SCHEMBL4181834 0.83 PPARD (0.86) PPARDPPARA
SCHEMBL4181742 0.83 PPARD (1.00) PPARDPPARA
SCHEMBL4174438 0.83 PPARD (1.00) PPARDPPARA
SCHEMBL4187308 0.83 PPARD (1.00) PPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090054493-A1 THIAZOLE DERIVATIVES AS PPAR DELTA LIGANDS AND THEIR MANUFACTURING PROCESS Kang, Heonjoong Kang (KR) 2009-02-26 US disclosed
CN-101146784-A Thiazole derivatives as PPAR delta ligands and manufacturing process thereof KANG HEONJOONG (KR) 2008-03-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054493-A1 THIAZOLE DERIVATIVES AS PPAR DELTA LIGANDS AND THEIR MANUFACTURING PROCESS PPARD, PPARG, PPARA PPARD 1/4885PPARA 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.