Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7248583 | 0.98 | ALDH1A1 (0.35) | ALDH1A1TSHRKDM4ETHRBPOLB | |
| SCHEMBL6580928 | 0.98 | ALDH1A1 (0.35) | ALDH1A1TSHRKDM4ETHRBPOLB | |
| SCHEMBL2418120 | 0.95 | — | — | |
| SCHEMBL9176896 | 0.93 | ALDH1A1 (0.35) | ALDH1A1TSHRKDM4ETHRBPOLB | |
| SCHEMBL27905163 | 0.87 | MEN1 (0.42) | ALDH1A1TSHRTHRBCES2 | |
| SCHEMBL2653 | 0.84 | — | — | |
| SCHEMBL4394009 | 0.83 | TSHR (0.46) | ALDH1A1TSHRTHRBCES2 | |
| SCHEMBL7249039 | 0.83 | HTT (0.37) | TSHRTHRBCES2EPHX2 | |
| SCHEMBL4396264 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRTHRB | |
| SCHEMBL3670957 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8354439-B2 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-15 | — | — | US | disclosed |
| US-20090221458-A1 | SUCCINIC ACID SEMI-AMIDES AS ANTI-CORROSIVE AGENTS | CAMENZIND HUGO | 2009-09-03 | — | — | US | disclosed |
| US-20070238758-A1 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | OTSUKA PHARMACEUTICAL CO., LTD. | 2007-10-11 | — | — | US | disclosed |
| US-20070105911-A1 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | CHIHIRO MASATOSHI | 2007-05-10 | — | — | US | disclosed |
| US-7202016-B2 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2007-04-10 | — | — | US | disclosed |
| US-20050267003-A1 | Succinic acid semi-amides as anti-corrosives agents | CIBA SPECIALTY CHEMICALS CORP. | 2005-12-01 | — | — | US | disclosed |
| US-20050214680-A1 | Radiation-sensitive resin composition | MIYAJI MASAAKI | 2005-09-29 | — | — | US | disclosed |
| US-6933094-B2 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2005-08-23 | — | — | US | disclosed |
| EP-1130017-B1 | Azole derivatives and their use as superoxide radical inhibitors | OTSUKA PHARMA CO LTD (JP) | 2005-06-15 | — | — | EP | disclosed |
| EP-1539677-A2 | SUCCINIC ACID SEMI-AMIDES AS ANTI-CORROSIVES AGENTS | Ciba SC Holding AG (CH) | 2005-06-15 | — | — | EP | disclosed |
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| US-4994564-A | Dyeing synthetic fibers in shades of red, yellow | BASF AKTIENGESELLSCHAFT (DE) | 1991-02-19 | — | — | US | disclosed |
| EP-0207097-B1 | NEW CARBONIC ACID ESTERS | CIBA-GEIGY AG (CH) | 1990-08-08 | — | — | EP | disclosed |
| EP-0315899-A2 | Thien-3-yl azo dyes | BASF Aktiengesellschaft (DE) | 1989-05-17 | — | — | EP | disclosed |
| US-4764523-A | Novel carbonic acid esters | CIBA-GEIGY CORPORATION (US) | 1988-08-16 | — | — | US | disclosed |
| EP-0207097-A1 | NEW CARBONIC ACID ESTERS. | CIBA GEIGY AG (CH) | 1987-01-07 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |
| WO-1986003747-A1 | NEW CARBONIC ACID ESTERS | CIBA-GEIGY AG (CH) | 1986-07-03 | — | — | WO | disclosed |
| US-4415494-A | BLUE-TO-BLACK COLORFAST DISPERSE, NITRO DYES; DIAZOTIZING A P-NITROANILINE AND COUPLING WITH AN N-SUBSTITUTED 1-NAPHTHYLAMINE | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-11-15 | — | — | US | disclosed |
| EP-0036545-A1 | Water insoluble monoazo dyes, their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1981-09-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238758-A1 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | IL2, IL1RN, SELL | ALDH1A1 134/4885TSHR 724/4885KDM4E 3406/4885 |
| US-20070105911-A1 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | IL2, IL1RN, SELL | ALDH1A1 139/4885TSHR 742/4885KDM4E 3397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.