SCHEMBL4183409

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4185578	0.85	KDM4E (0.43)	CA12CA1CA7CA14CA2
	SCHEMBL27505130	0.80	POLB (0.41)	POLBPDE4DTSHRTDP1MTNR1A
	SCHEMBL2934916	0.79	IAPP (0.67)	IAPPPOLBTSHRCA12CA1
	SCHEMBL29852765	0.78	NPC1 (0.52)	IAPPTSHRCA12CA1CA7
	SCHEMBL607310	0.78	NPC1 (0.52)	IAPPTSHRCA12CA1CA7
	SCHEMBL27480879	0.78	POLB (0.40)	POLBPDE4DTSHRTDP1MTNR1A
	SCHEMBL13774982	0.77	PDE4D (0.36)	POLBPDE4DTSHRTDP1MTNR1A
	SCHEMBL4182931	0.77	POLB (0.38)	POLBPDE4DTSHRTDP1MTNR1A
	SCHEMBL16318855	0.77	IAPP (0.47)	IAPPPOLBTSHRCA12CA1
	SCHEMBL27698666	0.77	TDP1 (0.43)	POLBPDE4DTSHRCA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.