SCHEMBL4185578

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4183409	0.85	IAPP (0.42)	KDM4ECA12CA1CA2CA7
	SCHEMBL31062474	0.85	LDHA (0.44)	KDM4EALDH1A1HPGDTTR
	SCHEMBL25285645	0.77	IAPP (0.51)	KDM4ECA12CA1CA2CA7
	SCHEMBL392976	0.77	AKR1B1 (0.61)	KDM4ECA12CA1CA2CA7
	SCHEMBL30311288	0.77	AKR1B1 (0.61)	KDM4ECA12CA1CA2CA7
	SCHEMBL17080017	0.76	KDM4E (0.46)	KDM4EEGFRALDH1A1GAAHPGD
	SCHEMBL31062262	0.76	CHRM3 (0.41)	KDM4ECFD
	SCHEMBL2981629	0.76	ALDH1A1 (0.50)	KDM4ECA12CA1CA2CA7
	Methane SCHEMBL9292057	0.75	AKR1B1 (0.59)	KDM4ECA12CA1CA2CA7
	SCHEMBL8147897	0.75	GABRA1 (0.52)	KDM4ECA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.