SCHEMBL4183452

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14531013	0.85	NPSR1 (0.52)	NPSR1CCR6HPGDKDM4EALDH1A1
	SCHEMBL2473673	0.84	NPSR1 (0.50)	NPSR1HPGDKDM4EALDH1A1TSHR
	SCHEMBL1014039	0.83	NPSR1 (0.42)	NPSR1HPGDKDM4EALDH1A1TSHR
	SCHEMBL12808519	0.83	NPSR1 (0.61)	NPSR1HPGDKDM4EALDH1A1TSHR
	SCHEMBL10774745	0.79	GAA (0.43)	NPSR1HPGDKDM4EALDH1A1TSHR
	SCHEMBL20153033	0.77	NPSR1 (0.48)	NPSR1CCR6HKDC1MAPTPKM
	SCHEMBL4191181	0.77	NPSR1 (0.39)	NPSR1HPGDKDM4EALDH1A1TSHR
	SCHEMBL4190066	0.76	DRD2 (0.37)	NPSR1HPGDKDM4ECYP11B1CYP11B2
	SCHEMBL5582368	0.76	HPGD (0.50)	NPSR1HPGDKDM4EALDH1A1KMT2A
	SCHEMBL19006400	0.76	KMT2A (0.44)	HPGDKDM4EALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.