SCHEMBL4184664

SCHEMBL4184664

C=C(C)C(=O)N1CCNC1=O

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.47
FAAH O00519 1/20 0.45
NAAA Q02083 1/20 0.45
ALDH1A1 P00352 2/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.40
HSD17B10 Q99714 1/20 0.40
GAA P10253 2/20 0.38
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
TSHR P16473 1/20 0.35
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
KMT2A Q03164 2/20 0.32
TDP1 Q9NUW8 1/20 0.31
GFER P55789 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4184795 0.74 TDP1 (0.32) TDP1
SCHEMBL10434774 0.74
SCHEMBL10434775 0.72
SCHEMBL1323848 0.72
SCHEMBL12764294 0.71 ITGB1 (0.38) POLBMAPTGAAKMT2AL3MBTL1
SCHEMBL6639420 0.70
Hydrochloric Acid SCHEMBL11592382 0.70 NPSR1 (0.53) NPSR1FAAHNAAAALDH1A1POLB
SCHEMBL134244 0.70
SCHEMBL13484119 0.70
SCHEMBL11586051 0.69 ALDH1A1 (0.54) NPSR1FAAHNAAAALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6031016-A A HOMOGENEOUS ONE-PACKAGE SOLUTION OF N-VINYL-2-PYRROLIDONE, VINYL ACETATE, VINYL METHYL ETHER, GLYCIDYL (METH)ACRYLATE OR ACRYLIC MONOMERS, A HYDROPHILIC COUPLING AGENT, A POLYETHYLENICALLY UNSATURATED CURING AGENT, PHOTOINITIATOR DEN-MAT CORPORATION (US) 2000-02-29 US claimed
US-5847020-A Dental adhesive comprising a homogeneous mixture of an unsaturated monomer a coupling agent a crosslinking agent and a photoinitiator DEN-MAT CORPORATION (US) 1998-12-08 US claimed
JP-7102209-A None JP disclosed
CN-116370687-B First-aid hemostatic tissue patch based on acrylic acid copolymer and preparation method thereof 四川大学 2023-08-04 CN disclosed
CN-116370687-A First-aid hemostatic tissue patch based on acrylic acid copolymer and preparation method thereof 四川大学 2023-07-04 CN disclosed
CN-112292423-B Aqueous dispersions of multistage polymer particles and methods for their preparation 陶氏环球技术有限责任公司 2022-11-04 CN disclosed
CN-110088150-B Aqueous polymer dispersion and aqueous coating composition comprising the same 陶氏环球技术有限责任公司 2021-04-16 CN disclosed
CN-112292423-A Aqueous dispersions of multistage polymer particles and method for the production thereof 陶氏环球技术有限责任公司 2021-01-29 CN disclosed
EP-1361246-B1 ORGANIC POLYMER AND NOVEL POLYMERIZABLE COMPOUND MITSUI CHEMICALS INC (JP) 2009-02-18 EP disclosed
US-6797805-B2 Organic polymers and novel polymerizable compounds MITSUI CHEMICALS, INC. (JP) 2004-09-28 US disclosed
EP-1361246-A1 ORGANIC POLYMER AND NOVEL POLYMERIZABLE COMPOUND Mitsui Chemicals, Inc. (JP) 2003-11-12 EP disclosed
US-20030166808-A1 Organic polymers and novel polymerizable compound MITSUI CHEMICALS, INC. (JP) 2003-09-04 US disclosed
JP-H07102209-A WATER-BASED CURABLE RESIN COMPOSITION DAINIPPON INK & CHEM INC 1995-04-18 JP disclosed
EP-0240370-B1 N-ACYL SUBSTITUTED CYCLIC UREAS SEQUA CORPORATION (US) 1991-03-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030166808-A1 Organic polymers and novel polymerizable compound PCNA, UTP18, ODC1 NPSR1 4727/4885FAAH 4303/4885NAAA 1662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.