Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011695 | 0.93 | FFAR1 (0.47) | FFAR1PTGESMEN1KMT2AL3MBTL1 | |
| SCHEMBL4019340 | 0.83 | FFAR1 (0.51) | FFAR1PTGESMEN1KMT2AL3MBTL1 | |
| SCHEMBL13945493 | 0.82 | FFAR1 (0.46) | FFAR1PTGESMEN1KMT2AL3MBTL1 | |
| SCHEMBL13957725 | 0.82 | IRAK4 (0.56) | FFAR1PTGESMEN1KMT2AL3MBTL1 | |
| SCHEMBL4041321 | 0.81 | PTPN11 (0.47) | FFAR1PTGESL3MBTL1IRAK4HSD17B10 | |
| SCHEMBL4799015 | 0.81 | LMNA (0.35) | KMT2ABRPF1IRAK4MAPTMAPK1 | |
| SCHEMBL4020950 | 0.81 | IRAK4 (0.42) | KMT2AIRAK4MAPTMAPK1ALDH1A1 | |
| SCHEMBL4634208 | 0.73 | LMNA (0.39) | MEN1KMT2AIRAK4MAPTGAA | |
| SCHEMBL30393778 | 0.73 | KDM4E (0.49) | KMT2AMAPTHSD17B10GAAMAPK1 | |
| SCHEMBL412460 | 0.73 | KDM4E (0.49) | KMT2AMAPTHSD17B10GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009013354-A1 | ARYLMETHYLENE SUBSTITUTED N-ACYL-β-AMINO ALCOHOLS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-01-29 | — | — | WO | disclosed |