Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 5/20 | 0.35 |
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4184897 | 1.00 | ITGB3 (0.40) | ITGB3ITGA2BALDH1A1HDAC8TSHR | |
| SCHEMBL13080807 | 0.85 | PPARA (0.43) | ITGB3ITGA2BALDH1A1TSHRCTSK | |
| SCHEMBL4179198 | 0.84 | LPAR3 (0.49) | ITGB3ITGA2BLPAR1LPAR3 | |
| SCHEMBL4178943 | 0.84 | LPAR3 (0.50) | ITGB3ITGA2BLPAR1LPAR3 | |
| SCHEMBL4187807 | 0.84 | LPAR3 (0.50) | ITGB3ITGA2BLPAR1LPAR3 | |
| SCHEMBL4195121 | 0.84 | LPAR3 (0.50) | ITGB3ITGA2BLPAR1LPAR3 | |
| SCHEMBL4185123 | 0.84 | LPAR3 (0.50) | ITGB3ITGA2BLPAR1LPAR3 | |
| SCHEMBL4190836 | 0.84 | LPAR3 (0.50) | ITGB3ITGA2BLPAR1LPAR3 | |
| SCHEMBL4187715 | 0.84 | LPAR3 (0.50) | ITGB3ITGA2BLPAR1LPAR3 | |
| SCHEMBL4190739 | 0.84 | LPAR3 (0.50) | ITGB3ITGA2BLPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8283339-B2 | Vinyl phosphonate lysophosphatidic acid receptor antagonists | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2012-10-09 | — | — | US | disclosed |
| US-20090197835-A1 | VINYL PHOSPHONATE LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197835-A1 | VINYL PHOSPHONATE LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | LPAR1, LPAR4, LPAR5 | ITGB3 2491/4885ITGA2B 1892/4885ALDH1A1 3714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.