SCHEMBL4185263

SCHEMBL4185263

CCCCCCC#CC(O)CN

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 3/20 0.44
PTPN7 P35236 4/20 0.41
HTT P42858 1/20 0.39
RECQL P46063 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
DNM1 Q05193 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10912609 0.83 HMGCR (0.46) HMGCRPTPN7RECQLTDP1
SCHEMBL31682154 0.83 HMGCR (0.46) HMGCRPTPN7RECQLTDP1
SCHEMBL9626686 0.83 HMGCR (0.58) HMGCRPTPN7
SCHEMBL28707678 0.82 HMGCR (0.45) HMGCRPTPN7RECQLTDP1
SCHEMBL7872938 0.81 HMGCR (0.44) HMGCRPTPN7RECQLTDP1
SCHEMBL7749492 0.79 PTPN7 (0.47) HMGCRPTPN7RECQLTDP1
SCHEMBL31112881 0.79 PTPN7 (0.47) HMGCRPTPN7RECQLTDP1
SCHEMBL30088469 0.79 PTPN7 (0.47) HMGCRPTPN7RECQLTDP1
SCHEMBL31314896 0.79 PTPN7 (0.47) HMGCRPTPN7RECQLTDP1
SCHEMBL29389418 0.79 PTPN7 (0.47) HMGCRPTPN7RECQLTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7214738-B2 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers ACUSHNET COMPANY (US) 2007-05-08 US claimed
US-20050009642-A1 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US claimed
US-20090137342-A1 Golf Ball Layers Formed of Polyurethane-Based and Polyurea-Based Compositions Incorporating Block Copolymers ACUSHNET COMPANY 2009-05-28 US disclosed
US-7429629-B2 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers ACUSHNET COMPANY (US) 2008-09-30 US disclosed
US-20070197724-A1 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers ACUSHNET COMPANY 2007-08-23 US disclosed
US-7217764-B2 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers ACUSHNET COMPANY (US) 2007-05-15 US disclosed
US-7214738-B2 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers ACUSHNET COMPANY (US) 2007-05-08 US disclosed
US-7211624-B2 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers ACUSHNET COMPANY (US) 2007-05-01 US disclosed
US-7202303-B2 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers ACUSHNET COMPANY (US) 2007-04-10 US disclosed
US-20050009642-A1 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US disclosed
US-20050009638-A1 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US disclosed
US-20050009637-A1 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US disclosed
US-20040262808-A1 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-12-30 US disclosed