Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 10/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
| ▸ | C1R | P00736 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KLK3 | P07288 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16431272 | 0.87 | C1R (0.65) | ELANEMEN1KMT2ANPC1MAPT | |
| SCHEMBL25054223 | 0.86 | C1R (0.63) | ELANEMEN1KMT2ANPC1MAPT | |
| SCHEMBL5257723 | 0.82 | C1R (0.58) | ELANEMEN1KMT2AMAPTC1R | |
| SCHEMBL4197820 | 0.82 | C1R (0.61) | ELANEMEN1KMT2ANPC1MAPT | |
| SCHEMBL5921486 | 0.81 | PKM (0.57) | ELANEMEN1KMT2ANPC1MAPT | |
| SCHEMBL9985296 | 0.80 | ELANE (0.64) | ELANEMEN1KMT2ANPC1MAPT | |
| SCHEMBL4192197 | 0.80 | C1R (0.71) | ELANEC1R | |
| SCHEMBL2816912 | 0.78 | C1R (0.69) | ELANEMEN1KMT2ANPC1MAPT | |
| SCHEMBL4194659 | 0.76 | C1R (0.72) | ELANEMEN1KMT2ANPC1C1R | |
| SCHEMBL1095684 | 0.76 | ELANE (1.00) | ELANEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756044-A1 | THERAPEUTIC COMPOUNDS | AstraZeneca AB (SE) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005115972-A1 | THERAPEUTIC COMPOUNDS | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | WO | disclosed |