Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | AKT2 | P31751 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2864002 | 0.82 | TDP1 (0.58) | AKT1AKT2NPC1RAB9AADORA2A | |
| SCHEMBL4187116 | 0.82 | KMT2A (0.53) | AKT1AKT2NPC1RAB9AADORA2A | |
| SCHEMBL2862813 | 0.80 | KMT2A (0.54) | AKT1AKT2NPC1RAB9AADORA2A | |
| SCHEMBL13172436 | 0.79 | MEN1 (0.58) | ADORA2AKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL2870008 | 0.79 | CYP1A1 (0.41) | AKT1AKT2NPC1RAB9ATNKS | |
| SCHEMBL2865549 | 0.78 | KDM4E (0.61) | NPC1RAB9AADORA2AKDM4EKMT2A | |
| SCHEMBL28037464 | 0.78 | KMT2A (0.53) | AKT1AKT2NPC1RAB9ATNKS | |
| SCHEMBL28037446 | 0.78 | KMT2A (0.53) | AKT1AKT2NPC1RAB9ATNKS | |
| SCHEMBL22969335 | 0.77 | KIF11 (0.52) | AKT1AKT2HDAC6NPC1RAB9A | |
| SCHEMBL29893132 | 0.77 | AKT1 (0.46) | AKT1AKT2HDAC6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1640402-B1 | DIAMINE HAVING QUINOXALINE UNIT, POLYIMIDE PRECURSOR, POLYIMIDE AND USE THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2009-02-11 | — | — | EP | disclosed |
| US-20060128937-A1 | Diamine having quinoxaline unit, polyimide precursor, polyimide and use thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2006-06-15 | — | — | US | disclosed |
| EP-1640402-A1 | DIAMINE HAVING QUINOXALINE UNIT, POLYIMIDE PRECURSOR, POLYIMIDE AND USE THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2006-03-29 | — | — | EP | disclosed |