Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27696374 | 0.82 | ALDH1A1 (0.50) | SRD5A2ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL28377134 | 0.80 | SRD5A2 (0.57) | SRD5A2KDM4EALDH1A1AKR1C3CYP2C8 | |
| SCHEMBL11231215 | 0.79 | SRD5A2 (0.59) | SRD5A2KDM4EALDH1A1PPARGPPARD | |
| SCHEMBL6854428 | 0.77 | MEN1 (0.58) | SRD5A2KDM4EALDH1A1AKR1C3MEN1 | |
| SCHEMBL27745360 | 0.75 | SRD5A2 (0.56) | SRD5A2KDM4EALDH1A1AKR1C3CYP2C8 | |
| SCHEMBL11220023 | 0.74 | SRD5A2 (0.54) | SRD5A2ALDH1A1PPARGPPARAHPGD | |
| SCHEMBL12337417 | 0.73 | ALDH1A1 (0.61) | SRD5A2KDM4EALDH1A1AKR1C3CYP2C8 | |
| SCHEMBL27677908 | 0.73 | AKR1C3 (0.47) | ALDH1A1AKR1C3GAA | |
| SCHEMBL4067662 | 0.72 | BCL2 (0.47) | KDM4EALDH1A1AKR1C3CYP2C8CYP2C9 | |
| SCHEMBL2518517 | 0.72 | KDM4E (0.70) | SRD5A2KDM4EALDH1A1AKR1C3CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403825-B1 | CHEMICAL AGENTS CAPABLE OF FORMING COVALENT 3-D NETWORKS | OXFORD ADVANCED SURFACES LTD (GB) | 2019-09-11 | — | — | EP | disclosed |
| US-9193678-B2 | Chemical agents capable of forming covalent 3-D networks | OXFORD ADVANCED SURFACES LTD (GB) | 2015-11-24 | — | — | US | disclosed |
| US-20120021223-A1 | CHEMICAL AGENTS CAPABLE OF FORMING COVALENT 3-D NETWORKS | OXFORD ADVANCED SURFACES LTD. (GB) | 2012-01-26 | — | — | US | disclosed |
| EP-2403825-A1 | CHEMICAL AGENTS CAPABLE OF FORMING COVALENT 3-D NETWORKS | Oxford Advanced Surfaces Ltd (GB) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010100410-A1 | CHEMICAL AGENTS CAPABLE OF FORMING COVALENT 3-D NETWORKS | OXFORD ADVANCED SURFACES LTD (GB) | 2010-09-10 | — | — | WO | disclosed |