SCHEMBL4185969

SCHEMBL4185969

CCCN(CCC)CCCS(=O)(=O)O

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.41
CA1 P00915 3/20 0.37
NPSR1 Q6W5P4 1/20 0.36
EPHX2 P34913 1/20 0.35
CA12 O43570 3/20 0.34
CA2 P00918 2/20 0.34
CA14 Q9ULX7 1/20 0.34
DRD2 P14416 1/20 0.34
DRD4 P21917 1/20 0.34
DRD3 P35462 1/20 0.34
CA9 Q16790 2/20 0.33
PTGS1 P23219 1/20 0.33
PDE4A P27815 1/20 0.33
LMNA P02545 1/20 0.33
SLC6A6 P31641 1/20 0.33
CYP2C19 P33261 1/20 0.33
BLM P54132 1/20 0.33
KDM5A P29375 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4185963 0.93 APP (0.39) APPCA1NPSR1EPHX2CA12
SCHEMBL17833359 0.91 NPSR1 (0.42) APPCA1NPSR1EPHX2CA12
SCHEMBL14750206 0.91 APP (0.41) APPCA1NPSR1EPHX2CA12
SCHEMBL29774219 0.91 APP (0.41) APPCA1NPSR1EPHX2CA12
SCHEMBL26140963 0.90 APP (0.37) APPCA1NPSR1EPHX2CA12
SCHEMBL16666053 0.88 APP (0.50) APPNPSR1PTGS1PDE4ALMNA
SCHEMBL16316707 0.87 EPHX2 (0.44) APPCA1EPHX2CA12CA2
SCHEMBL30949863 0.87 EPHX2 (0.44) APPCA1EPHX2CA12CA2
SCHEMBL8816521 0.87 EPHX2 (0.44) APPCA1EPHX2CA12CA2
SCHEMBL30949867 0.87 EPHX2 (0.44) APPCA1EPHX2CA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118922555-A Method for electrochemiluminescence detection 中尺度技术有限责任公司 2024-11-08 CN claimed
EP-4457359-A1 METHODS FOR ELECTROCHEMILUMINESCENCE DETECTION Meso Scale Technologies, LLC (US) 2024-11-06 EP claimed
US-20230279290-A1 COMPOSITIONS AND METHODS FOR ASSAY MEASUREMENTS MESO SCALE TECHNOLOGIES LLC (US) 2023-09-07 US claimed
WO-2023129884-A1 METHODS FOR ELECTROCHEMILUMINESCENCE DETECTION MESO SCALE TECHNOLOGIES, LLC. (US) 2023-07-06 WO claimed
US-20210109100-A1 KITS SUITABLE FOR USE IN ELECTROCHEMILUMINESCENCE METHODS AND METHODS OF EFFECTING A SPECIFIC-BINDING NON-WASH ASSAY MESO SCALE TECHNOLOGIES, LLC. (US) 2021-04-15 US claimed
US-10753934-B2 Kits suitable for use in electrochemiluminescence methods and methods of effecting a specific-binding non-wash assay MESO SCALE TECHNOLOGIES, LLC. (US) 2020-08-25 US claimed
EP-1436598-B1 ASSAY BUFFER, COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME MESO SCALE TECHNOLOGIES LLC (US) 2013-11-27 EP claimed
EP-1893990-A2 ELECTROCHEMISTRY AND ELECTROGENERATED CHEMILUMINESCENCE WITH A SINGLE FARADAIC ELECTRODE THE UNIVERSITY OF TEXAS SYSTEM (US) 2008-03-05 EP claimed
EP-1436598-A4 ASSAY BUFFER, COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME MESO SCALE TECHNOLOGIES LLC (US) 2007-10-31 EP claimed
WO-2007053191-A9 ELECTROCHEMISTRY AND ELECTROGENERATED CHEMILUMINESCENCE WITH A SINGLE FARADAIC ELECTRODE UNIV TEXAS (US) 2007-08-09 WO claimed
WO-2007053191-A2 ELECTROCHEMISTRY AND ELECTROGENERATED CHEMILUMINESCENCE WITH A SINGLE FARADAIC ELECTRODE UNIVERSITY OF TEXAS SYSTEM (US) 2007-05-10 WO claimed
US-6919173-B2 Electrochemiluminescence; kinases; phosphatases MESO SCALE TECHNOLOGIES, LLC. (US) 2005-07-19 US claimed
EP-1436598-A1 ASSAY BUFFER, COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME Meso Scale Technologies LLC (US) 2004-07-14 EP claimed
US-20030175803-A1 Electrochemiluminescence; kinases; phosphatases MESO SCALE TECHNOLOGIES, LLC. 2003-09-18 US claimed
WO-2003023380-A1 ASSAY BUFFER, COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME MESO SCALE TECHNOLOGIES, LLC (US) 2003-03-20 WO claimed
CN-118922555-A Method for electrochemiluminescence detection 中尺度技术有限责任公司 2024-11-08 CN disclosed
EP-4457359-A1 METHODS FOR ELECTROCHEMILUMINESCENCE DETECTION Meso Scale Technologies, LLC (US) 2024-11-06 EP disclosed
US-20050136048-A1 Electrochemiluminescence assays; aqueous reagent composition consisting of water, tripropylamine 50 mM-1000 mM and an electrolyte comprising a pH buffer selected from tris(hydroxymethyl)aminomethane and glycylglycine, pH of 6.5-8.5; improved sensitivity MESO SCALE TECHNOLOGIES, LLC. 2005-06-23 US disclosed
US-20050136497-A1 Comprisese water, piperazine-N,N'-bis(2-ethanesulfonic acid), electrolyte comprising buffer selected from tris(hydroxymethyl)aminomethane, glycylglycine and phosphate, phenyl ether-containing surfactant, and optionally preservative; electroluminescence MESO SCALE TECHNOLOGIES, LLC. 2005-06-23 US disclosed
US-20030175803-A1 Electrochemiluminescence; kinases; phosphatases MESO SCALE TECHNOLOGIES, LLC. 2003-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050136048-A1 Electrochemiluminescence assays; aqueous reagent composition consisting of water, tripropylamine 50 mM-1000 mM and an electrolyte comprising a pH buffer selected from tris(hydroxymethyl)aminomethane and glycylglycine, pH of 6.5-8.5; improved sensitivity GNMT, TET1, MPG APP 1527/4885CA1 363/4885NPSR1 3046/4885
US-20030175803-A1 Electrochemiluminescence; kinases; phosphatases PRKACA, DUSP3, PPP6C APP 3936/4885CA1 1568/4885NPSR1 4174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.