Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9462288 | 1.00 | PPARG (0.45) | PPARGTSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL5828433 | 1.00 | PPARG (0.45) | PPARGTSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL4182081 | 1.00 | PPARG (0.45) | PPARGTSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL4184936 | 1.00 | PPARG (0.45) | PPARGTSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL11363522 | 1.00 | PPARG (0.45) | PPARGTSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL10580595 | 0.91 | PPARG (0.44) | PPARGTSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL9849450 | 0.91 | PPARG (0.44) | PPARGTSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL9852394 | 0.90 | PPARG (0.43) | PPARGTSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL10903892 | 0.89 | PPARG (0.48) | PPARGTSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL4083717 | 0.89 | PPARG (0.43) | PPARGTSHRLMNAALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176837-A1 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | SONY CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-1907347-A2 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | Arcadia Pharmaceuticals Inc. (US) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007009083-A2 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | ACADIA PHARMACEUTICALS INC. (US) | 2007-01-18 | — | — | WO | disclosed |
| EP-1456229-A2 | METHOD FOR PREPARING ECHINOCANDIN DERIVATIVES | Aventis Pharma S.A. (FR) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003054001-A2 | METHOD FOR PREPARING ECHINOCANDIN DERIVATIVES AND THEIR COMPOSITIONS | AVENTIS PHARMA S.A. (FR) | 2003-07-03 | — | — | WO | disclosed |
| EP-0333760-B1 | CYANO-ALICYCLIC ESTERS AND LIQUID CRYSTAL COMPOSITIONS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN (GB) | 1992-07-01 | — | — | EP | disclosed |
| EP-0422996-A2 | Liquid crystal compound | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1991-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176837-A1 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | RARB, RARA, RARG | PPARG 46/4885TSHR 358/4885LMNA 4564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.