Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL690744 | 1.00 | MTTP (0.81) | MTTP | |
| SCHEMBL1620341 | 0.86 | MTTP (1.00) | MTTP | |
| Dirlotapide SCHEMBL37781 | 0.85 | MTTP (1.00) | MTTP | |
| Dirlotapide SCHEMBL691507 | 0.85 | MTTP (1.00) | MTTP | |
| SCHEMBL6315527 | 0.84 | MTTP (0.69) | MTTP | |
| SCHEMBL3165562 | 0.81 | MTTP (0.75) | MTTP | |
| Potassium SCHEMBL4200253 | 0.80 | MTTP (0.74) | MTTP | |
| SCHEMBL4200245 | 0.80 | MTTP (0.74) | MTTP | |
| Water SCHEMBL4196426 | 0.80 | MTTP (0.74) | MTTP | |
| SCHEMBL4200403 | 0.80 | MTTP (0.74) | MTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239865-A1 | DIBENZYL AMINE COMPOUNDS AND DERIVATIVES | PFIZER PRODUCTS INC. | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239865-A1 | DIBENZYL AMINE COMPOUNDS AND DERIVATIVES | APOB, LDLR, CETP | MTTP 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.