Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4186951 | 1.00 | KMT2A (0.64) | KMT2AALDH1A1TSHRHTTLMNA | |
| SCHEMBL4180372 | 0.82 | KMT2A (0.61) | KMT2AALDH1A1TSHRHTTLMNA | |
| SCHEMBL24040870 | 0.82 | ALDH1A1 (0.74) | KMT2AALDH1A1TSHRHTTLMNA | |
| SCHEMBL4182162 | 0.80 | KMT2A (0.77) | KMT2AALDH1A1TSHRHTTLMNA | |
| SCHEMBL4194203 | 0.79 | KMT2A (0.59) | KMT2AALDH1A1TSHRHTTLMNA | |
| SCHEMBL4609361 | 0.79 | ALDH1A1 (0.74) | KMT2AALDH1A1TSHRHTTLMNA | |
| SCHEMBL7441253 | 0.77 | KMT2A (0.56) | KMT2AALDH1A1TSHRHTTLMNA | |
| SCHEMBL7420609 | 0.76 | HTT (0.78) | KMT2AALDH1A1TSHRHTTLMNA | |
| SCHEMBL7419582 | 0.76 | PDE4A (0.78) | KMT2AALDH1A1TSHRHTTLMNA | |
| SCHEMBL4184408 | 0.75 | KMT2A (0.58) | KMT2AALDH1A1TSHRHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069302-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069302-A1 | CHEMICAL COMPOUNDS | TBXA2R, PDE4D, PDE4A | KMT2A 3729/4885ALDH1A1 669/4885TSHR 576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.