Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.32 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.32 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4183073 | 0.90 | NR1H3 (0.40) | MAPTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL13875608 | 0.89 | MAPT (0.37) | TLR7MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1766932 | 0.87 | TLR7 (0.36) | TLR7MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1766372 | 0.87 | MAPT (0.36) | TLR7MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1766705 | 0.83 | TLR7 (0.35) | TLR7MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4175359 | 0.79 | MAPT (0.39) | MAPTRAB9ANPC1KCNJ11RXFP1 | |
| SCHEMBL4181081 | 0.79 | PTGS1 (0.47) | MAPTSMN1; SMN2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL13875611 | 0.78 | MAPT (0.39) | MAPTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL1767144 | 0.78 | RXFP1 (0.40) | MAPTRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL4192114 | 0.78 | MEN1 (0.50) | MAPTRAB9ANPC1SMN1; SMN2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099204-A1 | Amide derivative, insecticide containing the same and method for application thereof as insecticide | MITSUI CHEMICALS, INC. (JP) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099204-A1 | Amide derivative, insecticide containing the same and method for application thereof as insecticide | CYP2E1, GSTA1, CYP2S1 | TLR7 3194/4885MAPT 4640/4885RAB9A 2449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.