⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096949 | 0.79 | POLB (0.43) | — | |
| SCHEMBL13846309 | 0.79 | — | — | |
| SCHEMBL26016142 | 0.79 | CYP4F2 (0.35) | — | |
| Hydrochloric Acid SCHEMBL3506265 | 0.77 | POLB (0.42) | — | |
| SCHEMBL31070129 | 0.77 | PRKCA (0.35) | — | |
| SCHEMBL15114242 | 0.77 | PRKCA (0.36) | — | |
| SCHEMBL4258156 | 0.77 | POLB (0.48) | — | |
| SCHEMBL681950 | 0.77 | PRKCA (0.46) | — | |
| SCHEMBL12972547 | 0.75 | NPSR1 (0.41) | — | |
| SCHEMBL12842576 | 0.75 | PRKCA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 619 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4958018-A | REACTING A 3-HALOMETHYL-3-CEPHEM WITH A LEAD REDUCING AGENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1990-09-18 | — | — | US | claimed |
| EP-4400503-A2 | NOVEL FXR (NR1H4) BINDING AND ACTIVITY MODULATING COMPOUNDS | Gilead Sciences, Inc. (US) | 2024-07-17 | — | — | EP | disclosed |
| CN-118354772-A | Method for treating head and neck cancer | 北京诺诚健华医药科技有限公司 | 2024-07-16 | — | — | CN | disclosed |
| WO-2024140687-A1 | S1PR2 REGULATOR AND USE THEREOF | 北京昌平实验室 | 2024-07-04 | — | — | WO | disclosed |
| CN-118255830-A | S1PR2 modulators and uses thereof | 北京昌平实验室 | 2024-06-28 | — | — | CN | disclosed |
| CN-115960109-B | Preparation and application of condensed ring SHP2 phosphatase inhibitor | 药雅科技(上海)有限公司 | 2024-06-25 | — | — | CN | disclosed |
| US-20240190864-A1 | Bruton's Tyrosine Kinase (BTK) INHIBITOR AND APPLICATION THEREOF | YA THERAPEUTICS INC (CN) | 2024-06-13 | — | — | US | disclosed |
| EP-3636628-B1 | 13-OXIDIZED INGENOL DERIVATIVE AND USE THEREOF | TIANJIN PHARMACEUTICAL DA REN TANG GROUP CORP LTD TRADITIONAL CHINESE MEDICINE RES INSTITUTE (CN) | 2024-05-29 | — | — | EP | disclosed |
| WO-2024097897-A1 | LXR MODULATORS WITH BICYCLIC CORE MOIETY FOR TREATING DYSLIPIDEMIAS | ORSOBIO, INC. (US) | 2024-05-10 | — | — | WO | disclosed |
| WO-2024088069-A1 | PREPARATION FOR AROMATIC KRAS MUTANT PROTEIN INHIBITOR AND USE THEREOF | 药雅科技(上海)有限公司 | 2024-05-02 | — | — | WO | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0341694-B1 | Method for production of 3-exomethylenecepham derivatives | OTSUKA KAGAKU KK (JP) | 1995-09-06 | — | — | EP | disclosed |
| US-5436242-A | Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof for inhibiting blood platelet aggregation | SANKYO COMPANY, LIMITED (JP) | 1995-07-25 | — | — | US | disclosed |
| US-5321166-A | Method for the production of aldehydes | HOFFMANN-LA ROCHE INC. (US) | 1994-06-14 | — | — | US | disclosed |
| US-5288726-A | Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation | UBE INDUSTRIES LIMITED (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0559034-A2 | Process for the preparation of aldehydes | F. HOFFMANN-LA ROCHE AG (CH) | 1993-09-08 | — | — | EP | disclosed |
| EP-0542411-A2 | Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation | Sankyo Company Limited (JP) | 1993-05-19 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |
| US-4958018-A | REACTING A 3-HALOMETHYL-3-CEPHEM WITH A LEAD REDUCING AGENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1990-09-18 | — | — | US | disclosed |
| EP-0341694-A2 | Method for production of 3-exomethylenecepham derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1989-11-15 | — | — | EP | disclosed |