Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.75 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6401505 | 1.00 | ALDH1A1 (0.75) | ALDH1A1PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL6405047 | 1.00 | ALDH1A1 (0.75) | ALDH1A1PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL6398621 | 1.00 | ALDH1A1 (0.75) | ALDH1A1PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL2696845 | 1.00 | ALDH1A1 (0.75) | ALDH1A1PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL6399799 | 1.00 | ALDH1A1 (0.75) | ALDH1A1PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL6404665 | 1.00 | ALDH1A1 (0.75) | ALDH1A1PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL4181209 | 1.00 | ALDH1A1 (0.75) | ALDH1A1PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL271926 | 1.00 | ALDH1A1 (0.75) | ALDH1A1PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL6406012 | 1.00 | ALDH1A1 (0.75) | ALDH1A1PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL6405092 | 1.00 | ALDH1A1 (0.75) | ALDH1A1PRSS1PRSS2PRSS3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501830-A1 | 7-ARYL-3,9-DIAZABICYCLO[3.3.1]NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES | Actelion Pharmaceuticals Ltd. (CH) | 2005-02-02 | — | — | EP | claimed |
| WO-2003093267-A1 | 7-ARYL-3,9-DIAZABICYCLO(3.3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-11-13 | — | — | WO | claimed |
| CN-116981742-A | Antifouling coating composition | 日东化成株式会社 | 2023-10-31 | — | — | CN | disclosed |
| EP-1452865-B1 | COMPOSITION FOR BLOOD SERUM OR PLASMA SEPARATION AND VESSEL FOR BLOOD EXAMINATION CONTAINING THE SAME | SEKISUI CHEMICAL CO LTD (JP) | 2009-02-18 | — | — | EP | disclosed |
| US-7090970-B2 | Composition for blood serum or plasma separation and vessel for blood examination containing the same | SEKISUI CHEMICAL CO., LTD. (JP) | 2006-08-15 | — | — | US | disclosed |
| EP-1452865-A1 | COMPOSITION FOR BLOOD SERUM OR PLASMA SEPARATION AND VESSEL FOR BLOOD EXAMINATION CONTAINING THE SAME | SEKISUI CHEMICAL CO., LTD. (JP) | 2004-09-01 | — | — | EP | disclosed |
| US-20040129631-A1 | Composition for blood serum or plasma separation and vessel for blood examination containing the same | SEKISUI CHEMICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |