Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.72 |
| ▸ | PGR | P06401 | 1/20 | 0.72 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4025056 | 0.89 | AR (0.72) | ARPGRHDAC1 | |
| SCHEMBL4196099 | 0.89 | AR (0.66) | ARPGR | |
| SCHEMBL31743441 | 0.88 | AR (0.68) | ARPGRHDAC1 | |
| SCHEMBL4204207 | 0.88 | AR (0.82) | ARPGRHDAC1 | |
| SCHEMBL8924917 | 0.88 | AR (0.56) | ARPGRHDAC1 | |
| SCHEMBL8926413 | 0.86 | AR (0.53) | ARPGRHDAC1 | |
| SCHEMBL633929 | 0.86 | AR (0.88) | ARPGRHDAC1 | |
| SCHEMBL4195979 | 0.85 | AR (0.67) | ARPGRHDAC1 | |
| SCHEMBL2694365 | 0.85 | AR (0.94) | ARPGR | |
| SCHEMBL27966873 | 0.85 | AR (0.76) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097996-A1 | USE OF SUBSTITUTED PHENYLIMIDAZOLIDINES FOR PRODUCING MEDICAMENTS FOR TREATING METABOLIC SYNDROME | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |
| US-6162444-A | Cosmetic or pharmaceutical compositions | HOECHST MARION ROUSSEL (FR) | 2000-12-19 | — | — | US | disclosed |
| US-RE35956-E | Phenylimidazolidines having antiandrogenic activity | ROUSSEL UCLAF (FR) | 1998-11-10 | — | — | US | disclosed |
| US-5627201-A | Phenylimidazolidines having antiandrogenic activity | ROUSSEL UCLAF (FR) | 1997-05-06 | — | — | US | disclosed |
| US-5411981-A | Phenylimidazolidines having antiandrogenic activity | ROUSSEL UCLAF (FR) | 1995-05-02 | — | — | US | disclosed |