Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8926413 | 0.91 | AR (0.53) | ARPGRHDAC1 | |
| SCHEMBL8926566 | 0.88 | AR (0.64) | ARPGRHDAC1 | |
| SCHEMBL4189953 | 0.88 | AR (0.72) | ARPGRHDAC1 | |
| SCHEMBL7819446 | 0.85 | AR (0.73) | ARPGRHDAC1 | |
| SCHEMBL633896 | 0.80 | AR (0.67) | ARPGRHDAC1 | |
| SCHEMBL4025056 | 0.79 | AR (0.72) | ARPGRHDAC1 | |
| SCHEMBL4196099 | 0.79 | AR (0.66) | ARPGR | |
| SCHEMBL8924486 | 0.78 | AR (0.62) | ARPGRHDAC1 | |
| SCHEMBL3490509 | 0.77 | AR (0.56) | ARPGRHDAC1 | |
| SCHEMBL31743441 | 0.77 | AR (0.68) | ARPGRHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646172-A | Method of inducing antiandrogenic activity using imidazolidines substituted with a heterocycle | ROUSSEL UCLAF (FR) | 1997-07-08 | — | — | US | disclosed |