Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OAT | P04181 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12929618 | 1.00 | GABRR1 (0.36) | GABRR1TSHRMAPK1HSD17B10TDP1 | |
| SCHEMBL320499 | 0.70 | — | — | |
| SCHEMBL799755 | 0.70 | GABRR1 (0.36) | GABRR1TSHRMAPK1HSD17B10TDP1 | |
| SCHEMBL218786 | 0.70 | GABRR1 (0.36) | GABRR1TSHRMAPK1HSD17B10TDP1 | |
| SCHEMBL14439278 | 0.70 | GABRR1 (0.36) | GABRR1TSHRMAPK1HSD17B10TDP1 | |
| SCHEMBL21757620 | 0.70 | GABRR1 (0.36) | GABRR1TSHRMAPK1HSD17B10TDP1 | |
| SCHEMBL4918511 | 0.68 | — | — | |
| SCHEMBL4926639 | 0.68 | — | — | |
| SCHEMBL4918519 | 0.68 | — | — | |
| SCHEMBL14293551 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220056488-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE | GENOMATICA INC (US) | 2022-02-24 | — | — | US | disclosed |
| US-10793882-B2 | Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene | GENOMATICA, INC. (US) | 2020-10-06 | — | — | US | disclosed |
| EP-3312284-A2 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE | Genomatica, Inc. (US) | 2018-04-25 | — | — | EP | disclosed |
| US-20170335352-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE | AGAIN BIO APS (DK) | 2017-11-23 | — | — | US | disclosed |
| EP-2607340-B1 | Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene | GENOMATICA INC (US) | 2017-09-06 | — | — | EP | disclosed |
| US-9556461-B2 | Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene | GENOMATICA, INC. (US) | 2017-01-31 | — | — | US | disclosed |
| US-20150064750-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE | GENOMATICA, INC. (US) | 2015-03-05 | — | — | US | disclosed |
| US-8715957-B2 | Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene | GENOMATICA, INC. (US) | 2014-05-06 | — | — | US | disclosed |
| EP-2607340-A1 | Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene | Genomatica, Inc. (US) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012018624-A2 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE | GENOMATICA, INC. (US) | 2012-02-09 | — | — | WO | disclosed |
| US-20120021478-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE | AGAIN BIO APS (DK) | 2012-01-26 | — | — | US | disclosed |