SCHEMBL218786

SCHEMBL218786

O=C(O)C1=CC(=O)[C@@H](O)[C@H](O)C1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 1/20 0.36
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
THRB P10828 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
KMT2A Q03164 1/20 0.33
OAT P04181 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14439278 1.00 GABRR1 (0.36) GABRR1TSHRMAPK1HSD17B10TDP1
SCHEMBL21757620 1.00 GABRR1 (0.36) GABRR1TSHRMAPK1HSD17B10TDP1
SCHEMBL799755 1.00 GABRR1 (0.36) GABRR1TSHRMAPK1HSD17B10TDP1
SCHEMBL29550605 0.83 GABRR1 (0.42) GABRR1TSHRMAPK1HSD17B10TDP1
SCHEMBL20363529 0.82 GABRR1 (0.33) GABRR1TSHRMAPK1HSD17B10TDP1
SCHEMBL416062 0.82 GABRR1 (0.33) GABRR1TSHRMAPK1HSD17B10TDP1
SCHEMBL17453292 0.79 GABRR1 (0.32) GABRR1TSHRMAPK1HSD17B10TDP1
SCHEMBL419019 0.70 GABRR1 (0.36) GABRR1TSHRMAPK1HSD17B10TDP1
SCHEMBL12929618 0.70 GABRR1 (0.36) GABRR1TSHRMAPK1HSD17B10TDP1
SCHEMBL19215291 0.68 NOS3 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 731 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260097105-A1 SYSTEMS, FORMULATIONS AND METHODS FOR GENERATING UNIVERSAL PEPTIDE/MHC COMPLEXES WITH ENGINEERED DISULFIDE CONNECTING THE HEAVY AND LIGHT CHAINS CHILDRENS HOSPITAL PHILADELPHIA (US) 2026-04-09 US claimed
EP-4720317-A1 BIOLOGICAL ANISOLE PRODUCTION Wageningen Universiteit (NL) 2026-04-08 EP claimed
EP-4687989-A1 PROTEIN TYROSINE PHOSPHATASE WEDGE DOMAIN PEPTIDE DIMER FOR NERVOUS SYSTEM REPAIR Nervgen Pharma Corp. (CA) 2026-02-11 EP claimed
EP-4617282-A1 MEMBRANE FUSION INHIBITOR FOR INHIBITING AIDS VIRUS AND DRUG-RESISTANT STRAIN THEREOF, AND PHARMACEUTICAL USE THEREOF Institute Of Pathogen Biology, Chinese Academy Of Medical Sciences (CN) 2025-09-17 EP claimed
CN-119372167-A Escherichia coli-derived shikimate dehydrogenase mutant and method for producing shikimate 福建师范大学 2025-01-28 CN claimed
US-20250019728-A1 METHOD FOR PRODUCING AROMATIC COMPOUND KAO CORPORATION (JP) 2025-01-16 US claimed
CN-119242722-A Method for preparing shikimic acid or improving shikimic acid yield 福建师范大学 2025-01-03 CN claimed
CN-119193446-A Recombinant strain for producing 3-dehydroshikimic acid escherichia coli, construction method and application 山东阳成协盈生物技术有限责任公司 2024-12-27 CN claimed
CN-119177201-A Recombinant engineering bacterium for producing aromatic amino acid and construction method and application thereof 中国科学院天津工业生物技术研究所 2024-12-24 CN claimed
WO-2024253523-A1 BIOLOGICAL ANISOLE PRODUCTION WAGENINGEN UNIVERSITEIT (NL) 2024-12-12 WO claimed
US-20060241078-A1 Pharmaceutical compositions comprising a contraceptive agent in solution and a teratogen AHMED SALAH U 2006-10-26 US claimed
WO-2006023496-A2 VAGINAL CREAM COMPOSITIONS, KITS THEREOF AND METHODS OF USING THEREOF DURAMED PHARMACEUTICALS, INC. (US) 2006-03-02 WO claimed
US-20060040904-A1 Vaginal cream compositions, kits thereof and methods of using thereof DURAMED PHARMACEUTICALS, INC. 2006-02-23 US claimed
US-6472190-B1 CULTURING A HOST CELL CAPABLE OF CONVERTING THE CARBON SOURCE TO 3-DEHYDROSHIKIMIC ACID AND A RECOMBINANT DNA ENCODING AN ENZYME WHICH CONVERTS 3-DEHYDROSHIKIMIC ACID TO PROTOCATECHUIC ACID, AN ENZYME WHICH CONVERTS IT TO GALLIC ACID BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERISITY 2002-10-29 US claimed
EP-0934062-B1 ANTIOXIDANT ACTIVITY OF 3-DEHYDROSHIKIMATES UNIV MICHIGAN STATE (US) 2002-03-27 EP claimed
WO-2001071020-A2 BIOCATALYTIC SYNTHESIS OF GALLOID ORGANICS BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) 2001-09-27 WO claimed
EP-0934062-A4 ANTIOXIDANT ACTIVITY OF 3-DEHYDROSHIKIMATES UNIV MICHIGAN STATE (US) 2000-06-07 EP claimed
EP-0934062-A1 ANTIOXIDANT ACTIVITY OF 3-DEHYDROSHIKIMATES MICHIGAN STATE UNIVERSITY (US) 1999-08-11 EP claimed
US-5821266-A Antioxidant activity of 3-dehydroshinkimates MICHIGAN STATE UNIVERSITY (US) 1998-10-13 US claimed
WO-1998003169-A1 ANTIOXIDANT ACTIVITY OF 3-DEHYDROSHIKIMATES MICHIGAN STATE UNIVERSITY (US) 1998-01-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097105-A1 SYSTEMS, FORMULATIONS AND METHODS FOR GENERATING UNIVERSAL PEPTIDE/MHC COMPLEXES WITH ENGINEERED DISULFIDE CONNECTING THE HEAVY AND LIGHT CHAINS HLA-DRB1, MICA, FTH1 GABRR1 3545/4885TSHR 1149/4885MAPK1 1748/4885
US-20060241078-A1 Pharmaceutical compositions comprising a contraceptive agent in solution and a teratogen CYP19A1, CYP21A2, CYP17A1 GABRR1 946/4885TSHR 1339/4885MAPK1 4539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.