SCHEMBL419059

SCHEMBL419059

COc1ccc(S(=O)(=O)NN)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.66
CA2 P00918 1/20 0.66
MMP1 P03956 1/20 0.66
MMP2 P08253 1/20 0.66
MMP9 P14780 1/20 0.66
MMP8 P22894 1/20 0.66
MMP13 P45452 1/20 0.66
ALDH1A1 P00352 5/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
PKM P14618 2/20 0.59
F2 P00734 1/20 0.59
PRSS1 P07477 1/20 0.59
PRSS2 P07478 1/20 0.59
PRSS3 P35030 1/20 0.59
GAA P10253 2/20 0.57
FFAR4 Q5NUL3 3/20 0.56
CYP19A1 P11511 1/20 0.56
LMNA P02545 1/20 0.56
MAPK1 P28482 1/20 0.56
KEAP1 Q14145 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28083438 0.94 MMP2 (0.65) CA1CA2MMP1MMP2MMP9
SCHEMBL36774 0.83 SMN1; SMN2 (0.63) CA1CA2MMP1MMP2MMP9
SCHEMBL2788247 0.83 CA1 (0.70) CA1CA2MMP1MMP2MMP9
SCHEMBL6920363 0.83 MMP2 (0.70) CA1CA2MMP1MMP2MMP9
SCHEMBL1706125 0.82 SMN1; SMN2 (0.59) CA1CA2MMP1MMP2MMP9
SCHEMBL1620820 0.81 SMN1; SMN2 (0.73) CA1CA2MMP1MMP2MMP9
SCHEMBL12361571 0.81 MMP2 (0.68) CA1CA2MMP1MMP2MMP9
SCHEMBL11514815 0.79 SMN1; SMN2 (0.70) CA1CA2MMP1MMP2MMP9
SCHEMBL9241927 0.79 CA1 (0.66) CA1CA2MMP1MMP2MMP9
SCHEMBL8223998 0.79 MMP2 (1.00) CA1CA2MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 342 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117535689-A Method for synthesizing sulfonamide through decarbonylation of N, N-dimethylformamide and denitrification of sulfonyl hydrazide under electrochemical condition 湘潭大学 2024-02-09 CN claimed
EP-3670490-B1 METHOD OF PURIFYING PINE CHEMICAL COMPOSITIONS FROM ALDEHYDES KRATON POLYMERS LLC (US) 2023-01-18 EP claimed
CN-112409236-B Method for synthesizing 3-thioether indole with high selectivity 上海应用技术大学 2022-10-14 CN claimed
CN-110003160-B Osthole hydrazone/acylhydrazone/sulfonylhydrazone derivatives, and preparation method and application thereof 贵州中医药大学 2022-10-11 CN claimed
CN-112358424-B Preparation method of sulfinate compound 浙江工业大学 2022-06-21 CN claimed
CN-114318377-A Method for catalyzing olefin fluorosulfonation through electrochemistry 南京林业大学 2022-04-12 CN claimed
CN-111689883-B Synthetic method of diaryl sulfone compound 上海应用技术大学 2022-02-11 CN claimed
CN-114014859-A Triazole indolol compound and synthesis method thereof 绍兴文理学院 2022-02-08 CN claimed
CN-107915610-B Preparation method of cyclopentadecanone 万华化学集团股份有限公司 2021-03-09 CN claimed
CN-112409236-A Method for synthesizing 3-thioether indole with high selectivity 上海应用技术大学 2021-02-26 CN claimed
US-20200165191-A1 Method of Purifying Pine Chemical Compositions from Aldehydes KRATON POLYMERS LLC (US) 2020-05-28 US claimed
EP-3637524-A1 GELATINIZED SYSTEM AND APPLICATIONS IN LITHIUM AIR BATTERY, SUPER CAPACITOR OR CAPACITOR BATTERY IN ORGANIC SYSTEM Beijing Normal University (CN) 2020-04-15 EP claimed
EP-3637525-A1 FLEXIBLE ALL-SOLID-STATE LITHIUM-ION SECONDARY BATTERY AND MANUFACTURING METHOD THEREFOR Beijing Normal University (CN) 2020-04-15 EP claimed
US-20200099097-A1 GELABLE SYSTEM AND USES THEREOF IN LITHIUM-AIR BATTERIES, ORGANIC SUPERCAPACITORS OR CAPACITOR BATTERIES BEIJING NORMAL UNIVERSITY (CN) 2020-03-26 US claimed
US-20200099090-A1 FLEXIBLE ALL-SOLID-STATE LITHIUM-ION SECONDARY BATTERY AND PREPARATION METHOD THEREOF BEIJING NORMAL UNIVERSITY (CN) 2020-03-26 US claimed
CN-110698368-A Preparation method of (E) -3-phenyl-3-benzenesulfonyl acrylate compound 湖南大学 2020-01-17 CN claimed
CN-106420797-A Western medicine composition for treating xerophthalmia and preparation method thereof 郑州郑先医药科技有限公司 2017-02-22 CN claimed
CN-102492497-B Additive of M50 methanol gasoline HEBEI JICHUN ENERGY INVESTEMENT GROUP CO LTD 2014-08-27 CN claimed
CN-102492499-A Additive of M30 methanol gasoline XUEQIANG LI 2012-06-13 CN claimed
CN-102492497-A Additive of M50 methanol gasoline HEBEI JICHUN ENERGY INVESTEMENT GROUP CO LTD 2012-06-13 CN claimed