Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2425418 | 0.94 | KMT2A (0.54) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL2424314 | 0.94 | KMT2A (0.53) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL2421857 | 0.88 | KMT2A (0.52) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL7437813 | 0.87 | KMT2A (0.47) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL2423174 | 0.86 | KMT2A (0.59) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL3479955 | 0.86 | KMT2A (0.53) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL2428956 | 0.85 | KMT2A (0.53) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL6439275 | 0.85 | MEN1 (0.63) | KMT2AMEN1ALDH1A1POLBLMNA | |
| SCHEMBL2422077 | 0.84 | KMT2A (0.53) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL2428546 | 0.84 | KMT2A (0.55) | KMT2AMEN1PKMNPC1APOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026802-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | Laboratoires Serono SA (CH) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007141224-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | LABORATOIRES SERONO SA (CH) | 2007-12-13 | — | — | WO | disclosed |