Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2424314 | 0.93 | KMT2A (0.53) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL2420500 | 0.93 | KMT2A (0.51) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL2421857 | 0.90 | KMT2A (0.52) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL4968428 | 0.88 | MEN1 (0.44) | KMT2AMEN1ALDH1A1POLBLMNA | |
| SCHEMBL4190631 | 0.87 | KMT2A (0.49) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL2423025 | 0.87 | KMT2A (0.50) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL2422541 | 0.87 | KMT2A (0.56) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL7440613 | 0.86 | KMT2A (0.44) | KMT2AMEN1ALDH1A1MAPTCCR2 | |
| SCHEMBL2423174 | 0.86 | KMT2A (0.59) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL2429271 | 0.85 | KMT2A (0.53) | KMT2AMEN1PKMNPC1APOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2002-07-03 | — | — | EP | claimed |
| WO-2001023378-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | claimed |