⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30349410 | 0.96 | — | — | |
| SCHEMBL102 | 0.96 | — | — | |
| SCHEMBL30349526 | 0.96 | — | — | |
| SCHEMBL15544478 | 0.96 | — | — | |
| SCHEMBL4361674 | 0.96 | — | — | |
| SCHEMBL87532 | 0.96 | — | — | |
| SCHEMBL15545054 | 0.96 | — | — | |
| SCHEMBL30558016 | 0.96 | — | — | |
| SCHEMBL23071466 | 0.93 | — | — | |
| Ammonia Solution, Strong SCHEMBL1205837 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104119285-A | Compound used as estrogen-related receptor regulator and application of compound | GUANGZHOU INST BIOMED & HEALTH | 2014-10-29 | — | — | CN | claimed |
| WO-2023149739-A1 | CROSSLINKED COPOLYMER, POLYMER MEMBRANE COMPRISING SAME, AND ANION EXCHANGE MEMBRANE COMPRISING POLYMER MEMBRANE | 한화솔루션 주식회사 | 2023-08-10 | — | — | WO | disclosed |
| CN-116082573-A | Beta-cyclodextrin-polyacrylamide hydrogel based on covalent organic framework, and preparation method and application thereof | 江南大学 | 2023-05-09 | — | — | CN | disclosed |
| CN-109851784-B | Method for preparing 1, 4-stereoregular polytriazole under catalysis of ruthenium complex | 华南理工大学 | 2021-06-08 | — | — | CN | disclosed |
| US-10898474-B2 | Anti-fibrotic pyridinones | INTERMUNE, INC. (US) | 2021-01-26 | — | — | US | disclosed |
| EP-2903991-B1 | ANTI-FIBROTIC PYRIDINONES | INTERMUNE INC (US) | 2020-09-16 | — | — | EP | disclosed |
| US-10544161-B2 | Anti-fibrotic pyridinones | INTERMUNE, INC. (US) | 2020-01-28 | — | — | US | disclosed |
| CN-110452216-A | Anti-fibrosis pyridinone | INTERMUNE INC | 2019-11-15 | — | — | CN | disclosed |
| US-20190321343-A1 | Anti-Fibrotic Pyridinones | GENENTECH, INC. | 2019-10-24 | — | — | US | disclosed |
| US-10376497-B2 | Anti-fibrotic pyridinones | INTERMUNE, INC. (US) | 2019-08-13 | — | — | US | disclosed |
| US-20040157909-A1 | 4-Aryl substituted indolinones | SUGEN, INC. | 2004-08-12 | — | — | US | disclosed |
| US-6677368-B2 | 4-aryl substituted indolinones | SUGEN, INC. | 2004-01-13 | — | — | US | disclosed |
| EP-1349852-A2 | 4-(HETERO)ARYL SUBSTITUTED INDOLINONES | Sugen, Inc. (US) | 2003-10-08 | — | — | EP | disclosed |
| US-6599902-B2 | For treating or preventing a protein kinase related disorder | SUGEN, INC. | 2003-07-29 | — | — | US | disclosed |
| US-20030125370-A1 | 5-ARALKYSUFONYL-3-(PYRROL-2-YLMETHYLIDENE)-2-INDOLINONE DERIVATIVES AS KINASE INHIBITORS | SUGEN, INC. | 2003-07-03 | — | — | US | disclosed |
| US-20030069297-A1 | 4-aryl substituted indolinones | SUGEN, INC. | 2003-04-10 | — | — | US | disclosed |
| WO-2002096361-A2 | 5-ARALKYLSULFONYL-3- (PYRROL-2-YLMETHYLIDENE)-2-INDOLINONE DERIVATIVES AS KINASE INHIBITORS | SUGEN, INC. (US) | 2002-12-05 | — | — | WO | disclosed |
| WO-2002055517-A2 | 4-(HETERO)ARYL SUBSTITUTED INDOLINONES | CUI JINGRONG (US) | 2002-07-18 | — | — | WO | disclosed |
| CN-1031239-C | Pesticide composition and application thereof | SHELL INT RESEARCH (NL) | 1996-03-13 | — | — | CN | disclosed |
| CN-86105384-A | 1-dimethylcarbamoyl-3-substituted-1H-1, 2, 4-triazoles | — | 1987-04-08 | — | — | CN | disclosed |